{"type":"research","record":{"id":3601,"source_id":"europe-pmc","external_id":"PMC13574142","title":"LSD1-mediated demethylation of the DNA damage response factor ATM promotes senescence and organ aging","authors":"Zhang Y, Yu C, Zhang X, Li L, Cheng A, Li X.","journal":null,"published_on":"2026-09-15","doi":null,"publication_type":null,"evidence_level":"research-record","source_url":"https://europepmc.org/article/PMC/PMC13574142","is_open_access":true,"cited_by_count":0,"editorial_summary":"Research record, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.","source_updated_at":"2026-09-16T06:17:12.522+00:00","first_seen_at":"2026-09-15T12:17:03.615746+00:00","last_seen_at":"2026-09-16T06:17:12.522+00:00","status":"published","metadata":{"pmid":null,"pmcid":"PMC13574142","source":"PMC","has_references":false},"integrity_checked_at":null,"abstract_text":null,"controlled_terms":["Aging","Cell biology","DNA repair","Cellular senescence","Cell Stress"],"relevance_confidence":65,"source_quality_score":90,"freshness_score":100,"publication_state":"published","match_explanation":"Source terminology contains: cellular senescence.","quality_checked_at":"2026-09-16T06:17:12.646875+00:00","duplicate_cluster_key":"title:lsd1-mediated-demethylation-dna-damage-response-factor-atm-promotes-senescence-organ-aging","duplicate_of_id":null,"research_item_topics":[{"topic_slug":"senolytics","is_published":true,"match_reasons":["Source terminology contains: cellular senescence.","Title supplies longevity context: aging, senescence."],"matched_fields":["controlled terminology","title context"],"relevance_score":65,"intelligence_topics":{"name":"Senolytics","slug":"senolytics"}}],"content_sources":{"name":"Europe PMC","homepage_url":"https://europepmc.org/"}},"canonical_url":"https://www.immortal.life/research/3601","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}