{"type":"research","record":{"id":5571,"source_id":"pubmed","external_id":"42634335","title":"Metformin in Neurodegenerative Diseases: Mechanisms and Therapeutic Implications.","authors":"Aveline P Langmead, Breauna A Keane, Jive A Jacob, Kota V Ramana","journal":"Current neuropharmacology","published_on":"2026-08-11","doi":"10.2174/011570159X476604260704180015","publication_type":"Journal Article","evidence_level":"research-record","source_url":"https://pubmed.ncbi.nlm.nih.gov/42634335/","is_open_access":null,"cited_by_count":null,"editorial_summary":"Research record published by Current neuropharmacology, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.","source_updated_at":"2026-09-16T06:17:22.206+00:00","first_seen_at":"2026-09-16T01:17:08.657654+00:00","last_seen_at":"2026-09-16T06:17:22.206+00:00","status":"published","metadata":{"pmid":"42634335","source":"NCBI PubMed E-utilities","mesh_terms":[]},"integrity_checked_at":"2026-09-16T06:17:16.341+00:00","abstract_text":"As the global burden of neurodegenerative disorders continues to rise with aging populations, there is growing interest…","controlled_terms":["Alzheimer’s disease","Metformin","Parkinson’s disease","diabetes","huntington’s disease","neurodegenerative disorders."],"relevance_confidence":100,"source_quality_score":95,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: metformin.","quality_checked_at":"2026-09-16T06:17:22.341306+00:00","duplicate_cluster_key":"id:10 2174 011570159x476604260704180015","duplicate_of_id":null,"research_item_topics":[{"topic_slug":"metformin","is_published":true,"match_reasons":["Title contains controlled term: metformin.","Source terminology contains: metformin.","Abstract supplies longevity context: aging."],"matched_fields":["title","controlled terminology","abstract context"],"relevance_score":100,"intelligence_topics":{"name":"Metformin","slug":"metformin"}}],"content_sources":{"name":"PubMed","homepage_url":"https://pubmed.ncbi.nlm.nih.gov/"}},"canonical_url":"https://www.immortal.life/research/5571","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}