{"type":"research","record":{"id":5627,"source_id":"pubmed","external_id":"41773040","title":"GLP-1 receptor agonists in older people with type 2 diabetes: safety evidence from the real world.","authors":"Marella Marassi, Gian Paolo Fadini","journal":"Expert opinion on drug safety","published_on":"2026-03-04","doi":"10.1080/14740338.2026.2640982","publication_type":"Journal Article; Review","evidence_level":"research-record","source_url":"https://pubmed.ncbi.nlm.nih.gov/41773040/","is_open_access":null,"cited_by_count":null,"editorial_summary":"Research record published by Expert opinion on drug safety, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.","source_updated_at":"2026-09-16T06:17:23.625+00:00","first_seen_at":"2026-09-16T01:17:10.167905+00:00","last_seen_at":"2026-09-16T06:17:23.625+00:00","status":"published","metadata":{"pmid":"41773040","source":"NCBI PubMed E-utilities","mesh_terms":["Humans","Diabetes Mellitus, Type 2","Glucagon-Like Peptide-1 Receptor Agonists","Hypoglycemic Agents","Aged","Age Factors","Weight Loss","Polypharmacy","Animals","Sarcopenia"]},"integrity_checked_at":"2026-09-16T06:17:16.341+00:00","abstract_text":"GLP-1 receptor agonists (GLP-1RA) are glucose- and body weight-lowering therapies provided with cardio-renal benefits.… We discuss the opportunities and challenges of GLP-1RA in older people with T2DM, focusing on real-world (RW) safety ev… Current RW evidence supports GLP-1RA as a safe therapeutic option for older individuals with T2DM, without age-specific…","controlled_terms":["Humans","Diabetes Mellitus, Type 2","Glucagon-Like Peptide-1 Receptor Agonists","Hypoglycemic Agents","Aged","Age Factors","Weight Loss","Polypharmacy","Animals","Sarcopenia","Diabetes","incretin","older","sarcopenia","weight"],"relevance_confidence":100,"source_quality_score":95,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: glp-1.","quality_checked_at":"2026-09-16T06:17:23.755824+00:00","duplicate_cluster_key":"id:10 1080 14740338 2026 2640982","duplicate_of_id":null,"research_item_topics":[{"topic_slug":"glp-1-therapies","is_published":true,"match_reasons":["Title contains controlled term: glp-1.","Abstract contains controlled term: glp-1.","Title supplies longevity context: older people."],"matched_fields":["title","abstract","title context"],"relevance_score":100,"intelligence_topics":{"name":"GLP-1 therapies","slug":"glp-1-therapies"}}],"content_sources":{"name":"PubMed","homepage_url":"https://pubmed.ncbi.nlm.nih.gov/"}},"canonical_url":"https://www.immortal.life/research/5627","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}