{"type":"research","record":{"id":5756,"source_id":"pubmed","external_id":"42437623","title":"The associations of trouble sleeping, biological age acceleration with depressive symptoms: Evidence from three cohorts.","authors":"Yanping Wu, Xianxin Xia, Ping Jing, Fei Ye, Qin Wang","journal":"Journal of affective disorders","published_on":"2026-07-12","doi":"10.1016/j.jad.2026.122255","publication_type":"Journal Article","evidence_level":"research-record","source_url":"https://pubmed.ncbi.nlm.nih.gov/42437623/","is_open_access":null,"cited_by_count":null,"editorial_summary":"Research record published by Journal of affective disorders, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.","source_updated_at":"2026-09-16T06:17:29.08+00:00","first_seen_at":"2026-09-16T01:17:15.049137+00:00","last_seen_at":"2026-09-16T06:17:29.08+00:00","status":"published","metadata":{"pmid":"42437623","source":"NCBI PubMed E-utilities","mesh_terms":["Humans","Depression","Aging","Female","Cross-Sectional Studies","Male","Cohort Studies","Sleep Wake Disorders","Nutrition Surveys"]},"integrity_checked_at":"2026-09-16T06:17:16.341+00:00","abstract_text":"This study investigates the relationship between trouble sleeping, biological age (BA) acceleration, and depressive sym… Data were utilized from three cohorts: NHANES, CHARLS, and HRS. Depressive symptoms were assessed using PHQ-9 or CES-D.… Trouble sleeping exhibited an association with higher odds of depressive symptoms (NHANES: OR = 4.714; CHARLS… In NHANES and HRS, the combined association of BA acceleration and trouble sleeping was associated with the highest odd…","controlled_terms":["Humans","Depression","Aging","Female","Cross-Sectional Studies","Male","Cohort Studies","Sleep Wake Disorders","Nutrition Surveys","Biological age acceleration","CHARLS","HRS","NHANES","Trouble sleeping"],"relevance_confidence":100,"source_quality_score":95,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: sleep.","quality_checked_at":"2026-09-16T06:17:29.196395+00:00","duplicate_cluster_key":"id:10 1016 j jad 2026 122255","duplicate_of_id":null,"research_item_topics":[{"topic_slug":"sleep","is_published":true,"match_reasons":["Title contains controlled term: sleep.","Abstract contains controlled term: sleep.","Source terminology contains: sleep.","Title supplies longevity context: biological age."],"matched_fields":["title","abstract","controlled terminology","title context"],"relevance_score":100,"intelligence_topics":{"name":"Sleep","slug":"sleep"}}],"content_sources":{"name":"PubMed","homepage_url":"https://pubmed.ncbi.nlm.nih.gov/"}},"canonical_url":"https://www.immortal.life/research/5756","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}