{"type":"research","record":{"id":5805,"source_id":"pubmed","external_id":"42564270","title":"Minimally processed, human-grade diet alters canine epigenetic ageing: Results from a pilot study.","authors":"Aimee Chen, Wei Guo, Janina A Krumbeck, Dan Su, Vincent Michels, Xiaojing Yang","journal":"Veterinary record open","published_on":"2026-08-05","doi":"10.1002/vro2.70047","publication_type":"Journal Article","evidence_level":"research-record","source_url":"https://pubmed.ncbi.nlm.nih.gov/42564270/","is_open_access":null,"cited_by_count":null,"editorial_summary":"Research record published by Veterinary record open, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.","source_updated_at":"2026-09-16T06:17:30.435+00:00","first_seen_at":"2026-09-16T01:17:16.555758+00:00","last_seen_at":"2026-09-16T06:17:30.435+00:00","status":"published","metadata":{"pmid":"42564270","source":"NCBI PubMed E-utilities","mesh_terms":[]},"integrity_checked_at":"2026-09-16T06:17:16.341+00:00","abstract_text":"Diet plays a critical role in promoting wellness and longevity in both humans and canines. Epigenetic ageing clocks hav… A dog-specific epigenetic ageing clock was developed and validated using buccal swab samples from domestic dogs aged 1.… Dogs fed with MPHGF diet exhibited a significant reduction in delta age, decreasing from 2.75 to 1.80 years over 6 mont… This study demonstrates the potential for dietary interventions to influence epigenetic ageing in dogs and provides a p…","controlled_terms":["DNA methylation","ageing","canine","epigenetic age","epigenetics","kibble diet","minimally processed diet"],"relevance_confidence":65,"source_quality_score":95,"freshness_score":100,"publication_state":"published","match_explanation":"Source terminology contains: dna methylation age.","quality_checked_at":"2026-09-16T06:17:30.534492+00:00","duplicate_cluster_key":"id:10 1002 vro2 70047","duplicate_of_id":null,"research_item_topics":[{"topic_slug":"epigenetic-clocks","is_published":true,"match_reasons":["Source terminology contains: dna methylation age.","Title supplies longevity context: ageing."],"matched_fields":["controlled terminology","title context"],"relevance_score":65,"intelligence_topics":{"name":"Epigenetic clocks","slug":"epigenetic-clocks"}}],"content_sources":{"name":"PubMed","homepage_url":"https://pubmed.ncbi.nlm.nih.gov/"}},"canonical_url":"https://www.immortal.life/research/5805","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}