{"type":"research","record":{"id":5825,"source_id":"pubmed","external_id":"42435241","title":"Accelerated aging in schizophrenia: integrating epigenetic clocks, telomere dynamics, senescence-associated secretory phenotype, and oxidative stress.","authors":"Xuan Ge, Chenying Jiang, Chaoran Wu, Xinyu Fang, Xiangrong Zhang","journal":"European archives of psychiatry and clinical neuroscience","published_on":"2026-07-11","doi":"10.1007/s00406-026-02325-8","publication_type":"Journal Article; Review","evidence_level":"research-record","source_url":"https://pubmed.ncbi.nlm.nih.gov/42435241/","is_open_access":null,"cited_by_count":null,"editorial_summary":"Research record published by European archives of psychiatry and clinical neuroscience, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.","source_updated_at":"2026-09-16T06:17:30.435+00:00","first_seen_at":"2026-09-16T01:17:16.555758+00:00","last_seen_at":"2026-09-16T06:17:30.435+00:00","status":"published","metadata":{"pmid":"42435241","source":"NCBI PubMed E-utilities","mesh_terms":["Humans","Oxidative Stress","Schizophrenia","Epigenesis, Genetic","Telomere","Aging","Senescence-Associated Secretory Phenotype","Aging, Premature"]},"integrity_checked_at":"2026-09-16T06:17:16.341+00:00","abstract_text":"Schizophrenia (SCZ) is a severe and chronic neuropsychiatric disorder associated with substantially shortened life expe…","controlled_terms":["Humans","Oxidative Stress","Schizophrenia","Epigenesis, Genetic","Telomere","Aging","Senescence-Associated Secretory Phenotype","Aging, Premature","Accelerated aging","Epigenetics","Oxidative stress","SASP","Telomeres"],"relevance_confidence":75,"source_quality_score":95,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: epigenetic clock.","quality_checked_at":"2026-09-16T06:17:30.534492+00:00","duplicate_cluster_key":"id:10 1007 s00406-026-02325-8","duplicate_of_id":null,"research_item_topics":[{"topic_slug":"epigenetic-clocks","is_published":true,"match_reasons":["Title contains controlled term: epigenetic clock.","Title supplies longevity context: aging, senescence."],"matched_fields":["title","title context"],"relevance_score":75,"intelligence_topics":{"name":"Epigenetic clocks","slug":"epigenetic-clocks"}}],"content_sources":{"name":"PubMed","homepage_url":"https://pubmed.ncbi.nlm.nih.gov/"}},"canonical_url":"https://www.immortal.life/research/5825","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}