{"type":"research","record":{"id":5883,"source_id":"pubmed","external_id":"42573713","title":"Mechanisms of Hematopoietic Stem Cell Aging and Emerging Rejuvenation Strategies.","authors":"Qi Liu, Lijun Zhao, Chengying Li","journal":"Stem cell reviews and reports","published_on":"2026-08-10","doi":"10.1007/s12015-026-11211-8","publication_type":"Journal Article; Review","evidence_level":"research-record","source_url":"https://pubmed.ncbi.nlm.nih.gov/42573713/","is_open_access":null,"cited_by_count":null,"editorial_summary":"Research record published by Stem cell reviews and reports, indexed because it matched monitored longevity research terms. Inclusion in this index does not establish that an intervention is effective or safe.","source_updated_at":"2026-09-16T06:17:34.651+00:00","first_seen_at":"2026-09-16T01:17:19.049304+00:00","last_seen_at":"2026-09-16T06:17:34.651+00:00","status":"published","metadata":{"pmid":"42573713","source":"NCBI PubMed E-utilities","mesh_terms":["Humans","Hematopoietic Stem Cells","Cellular Senescence","Rejuvenation","Animals","Aging","Epigenesis, Genetic"]},"integrity_checked_at":"2026-09-16T06:17:16.341+00:00","abstract_text":"Hematopoietic stem cell (HSCs) aging is a complex biological process driven by both cell-intrinsic alterations and extr…","controlled_terms":["Humans","Hematopoietic Stem Cells","Cellular Senescence","Rejuvenation","Animals","Aging","Epigenesis, Genetic","Bone marrow microenvironment","Hematopoietic stem cell"],"relevance_confidence":100,"source_quality_score":95,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: stem cell.","quality_checked_at":"2026-09-16T06:17:34.765074+00:00","duplicate_cluster_key":"id:10 1007 s12015-026-11211-8","duplicate_of_id":null,"research_item_topics":[{"topic_slug":"stem-cells","is_published":true,"match_reasons":["Title contains controlled term: stem cell.","Abstract contains controlled term: stem cell.","Source terminology contains: stem cell.","Title supplies longevity context: aging, rejuvenation."],"matched_fields":["title","abstract","controlled terminology","title context"],"relevance_score":100,"intelligence_topics":{"name":"Stem cells","slug":"stem-cells"}}],"content_sources":{"name":"PubMed","homepage_url":"https://pubmed.ncbi.nlm.nih.gov/"}},"canonical_url":"https://www.immortal.life/research/5883","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}