{"type":"trials","record":{"id":180,"source_id":"clinicaltrials-gov","external_id":"NCT07000708","title":"VITAL: Vaccination, Immunity, Time-restricted Eating, Aging and Lifestyle","brief_summary":"The aim of this study is to investigate the effects of a four-week time-restricted eating (TRE) intervention on autophagy, immune function, and vaccine response to a seasonal influenza and COVID-19 vaccines in older healthy subjects.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Charite University, Berlin, Germany","enrollment":24,"countries":["Germany"],"start_date":"2025-09-10","completion_date":"2027-01-01","last_update_date":"2025-09-18","source_url":"https://clinicaltrials.gov/study/NCT07000708","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-14T02:45:00.719473+00:00","last_seen_at":"2026-09-15T00:18:34.37+00:00","metadata":{"acronym":"VITAL","organization":"Charite University, Berlin, Germany","source_has_results":false},"controlled_terms":[],"relevance_confidence":80,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Published automatically with 80% topic confidence after controlled-term evaluation.","quality_checked_at":"2026-09-15T02:15:56.576005+00:00","duplicate_cluster_key":"registry:nct07000708","duplicate_of_id":null,"clinical_trial_topics":[{"topic_slug":"caloric-restriction","is_published":true,"match_reasons":["Legacy trial evaluated automatically against controlled title, summary, and longevity-context rules."],"matched_fields":["title"],"relevance_score":80,"intelligence_topics":{"name":"Caloric restriction","slug":"caloric-restriction"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/180","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}