{"type":"trials","record":{"id":184,"source_id":"clinicaltrials-gov","external_id":"NCT05786521","title":"Effect of GLP1 Receptor Agonists on Physical Function, Body Composition, and Markers of Aging in Older Adults","brief_summary":"Semaglutide is a medication approved by the US Food and Drug Administration (FDA) as an antihyperglycemic (a drug that reduces glucoses in those with diabetes) and for weight management. This new study will help find out what effects, semaglutide has on people who take the drug and the drug's effect on physical function, body composition, and aging.","overall_status":"Completed","phases":["PHASE4"],"study_type":"INTERVENTIONAL","sponsor":"The University of Texas Health Science Center at San Antonio","enrollment":20,"countries":["United States"],"start_date":"2023-04-01","completion_date":"2024-05-20","last_update_date":"2025-05-04","source_url":"https://clinicaltrials.gov/study/NCT05786521","editorial_summary":"A registered PHASE4 study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-14T02:45:00.719473+00:00","last_seen_at":"2026-09-15T00:18:33.541+00:00","metadata":{"acronym":null,"organization":"The University of Texas Health Science Center at San Antonio","source_has_results":true},"controlled_terms":[],"relevance_confidence":80,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Published automatically with 80% topic confidence after controlled-term evaluation.","quality_checked_at":"2026-09-15T02:15:56.576005+00:00","duplicate_cluster_key":"registry:nct05786521","duplicate_of_id":null,"clinical_trial_topics":[{"topic_slug":"glp-1-therapies","is_published":true,"match_reasons":["Legacy trial evaluated automatically against controlled title, summary, and longevity-context rules."],"matched_fields":["title"],"relevance_score":80,"intelligence_topics":{"name":"GLP-1 therapies","slug":"glp-1-therapies"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/184","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}