{"type":"trials","record":{"id":2,"source_id":"clinicaltrials-gov","external_id":"NCT07058974","title":"A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation","brief_summary":"This is a study assessing the feasibility of performing an anti-aging intervention which is a combination of an exercise regimen, spermidine supplementation, and either rapamycin or lamivudine.","overall_status":"Active Not Recruiting","phases":["PHASE1"],"study_type":"INTERVENTIONAL","sponsor":"Icahn School of Medicine at Mount Sinai","enrollment":20,"countries":["United States"],"start_date":"2025-08-12","completion_date":"2027-06-15","last_update_date":"2026-08-27","source_url":"https://clinicaltrials.gov/study/NCT07058974","editorial_summary":"A registered PHASE1 study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-14T02:44:58.543517+00:00","last_seen_at":"2026-09-15T00:18:31.508+00:00","metadata":{"acronym":null,"organization":"Icahn School of Medicine at Mount Sinai","source_has_results":false},"controlled_terms":[],"relevance_confidence":68,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Published automatically with 68% topic confidence after controlled-term evaluation.","quality_checked_at":"2026-09-15T02:15:56.576005+00:00","duplicate_cluster_key":"registry:nct07058974","duplicate_of_id":null,"clinical_trial_topics":[{"topic_slug":"rapamycin","is_published":true,"match_reasons":["Legacy trial evaluated automatically against controlled title, summary, and longevity-context rules."],"matched_fields":["abstract"],"relevance_score":68,"intelligence_topics":{"name":"Rapamycin","slug":"rapamycin"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/2","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}