{"type":"trials","record":{"id":21869,"source_id":"clinicaltrials-gov","external_id":"NCT07060898","title":"Impact of a Novel Brain Longevity Supplement Containing the Postbiotic Urolithin A (Mitopure) on Cognitive Function and Related Health Outcomes","brief_summary":"This is a parallel group, randomized, double-blind, placebo-controlled clinical study assessing the safety and effects of a novel nutritional product on self-reported cognitive function and health in adults that reside in the USA. Participants will take their assigned study product (active or placebo) for 8 weeks and answer validated electronic surveys assessing cognitive function delivered to them through a text message (SMS) link or through email.","overall_status":"Active Not Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Amazentis SA","enrollment":650,"countries":["United States"],"start_date":"2025-07-29","completion_date":"2026-11-20","last_update_date":"2026-03-06","source_url":"https://clinicaltrials.gov/study/NCT07060898","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-24T01:17:11.779627+00:00","last_seen_at":"2026-09-25T06:05:51.139+00:00","metadata":{"sex":"ALL","acronym":"CLARITY","age_range":"40 Years","comparator":"Active; Placebo","organization":"Amazentis SA","interventions":["Active Product","Placebo Product"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Cognitive function — 8 weeks","Fatigue — 8 weeks","Sleep-related impairment — 8 weeks","Cognitive abilities — 8 weeks","Cognitive function (brain health) via smartphone application assessments — 8 weeks","Minimal clinically important difference (MCID) in cognitive function — 8 weeks","Minimal clinically important difference (MCID) in fatigue — 8 weeks","Minimal clinically important difference (MCID) in sleep — 8 weeks","Minimal clinically important difference (MCID) in cognitive abilities — 8 weeks","Adverse Events — 8 weeks"],"design_description":"RANDOMIZED · PARALLEL · BASIC SCIENCE · QUADRUPLE","source_has_results":false},"controlled_terms":["Aging","Cognitive Decline","Brain Fog","Cognitive Function","Active Product","Placebo Product"],"relevance_confidence":80,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: urolithin a.","quality_checked_at":"2026-09-25T06:05:51.463359+00:00","duplicate_cluster_key":"id:nct07060898","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-07-29 to 2026-11-20","comparator":"Active; Placebo","confidence":"structured-source","population":"ALL · 40 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:05:51.141Z","intervention":["Active Product","Placebo Product"],"participants":650,"study_design":"RANDOMIZED · PARALLEL · BASIC SCIENCE · QUADRUPLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Cognitive function — 8 weeks","Fatigue — 8 weeks","Sleep-related impairment — 8 weeks","Cognitive abilities — 8 weeks","Cognitive function (brain health) via smartphone application assessments — 8 weeks","Minimal clinically important difference (MCID) in cognitive function — 8 weeks","Minimal clinically important difference (MCID) in fatigue — 8 weeks","Minimal clinically important difference (MCID) in sleep — 8 weeks","Minimal clinically important difference (MCID) in cognitive abilities — 8 weeks","Adverse Events — 8 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"urolithin-a","is_published":true,"match_reasons":["Title contains controlled term: urolithin a.","Title supplies longevity context: longevity.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Urolithin A","slug":"urolithin-a"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/21869","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}