{"type":"trials","record":{"id":21935,"source_id":"clinicaltrials-gov","external_id":"NCT05392582","title":"MicroRNA Regulation of Chronic Inflammation During Aging","brief_summary":"This is an observational study enrolling healthy individuals aged 18-35 and 65y and older to determine the health of immune cells in the blood and how these cells create inflammation and effect health as we age. It is hoped that once the nature of this relationship has been discovered we can more effectively design therapies to reduce this inflammation. The enrollment goal is 40 participants. The study will occur over the course of 1 month which will include a screening visit and a second visit where the participants will undergo an oral glucose tolerance test, blood draws and leg strength \\& exercise tests.","overall_status":"Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"University of Utah","enrollment":40,"countries":["United States"],"start_date":"2024-11-12","completion_date":"2028-01-01","last_update_date":"2025-12-05","source_url":"https://clinicaltrials.gov/study/NCT05392582","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-24T01:17:12.439005+00:00","last_seen_at":"2026-09-25T06:05:37.656+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"18 Years","comparator":null,"organization":"University of Utah","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["Inflammation — Determined in older adults and in younger adults at a single visit (baseline)."],"design_description":null,"source_has_results":false},"controlled_terms":["Chronic Inflammation"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: chronic inflammation.","quality_checked_at":"2026-09-25T06:05:39.423355+00:00","duplicate_cluster_key":"id:nct05392582","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-11-12 to 2028-01-01","comparator":null,"confidence":"structured-source","population":"ALL · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:05:37.665Z","intervention":[],"participants":40,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Inflammation — Determined in older adults and in younger adults at a single visit (baseline)."],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"chronic-inflammation","is_published":true,"match_reasons":["Title contains controlled term: chronic inflammation.","Source terminology contains: chronic inflammation.","Title supplies longevity context: aging.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Chronic inflammation","slug":"chronic-inflammation"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/21935","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}