{"type":"trials","record":{"id":22142,"source_id":"clinicaltrials-gov","external_id":"NCT03994562","title":"Determinants of Frailty Among of Informal Caregivers of Demented Patient","brief_summary":"Frailty, a transitional state between successful and pathological aging, may be benefit from early multi-interventional intervention. Fried's criteria are the more commonly used criteria to diagnose frailty. The caregivers' burden increases caregivers' morbidity .The main objective of the study was to assess the relationship between frailty among informal caregivers of demented patients and the caregiver's burden (Zarit scale). The Secondary objective was to assess determinants of frailty among caregivers.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Gérond'if","enrollment":120,"countries":["France"],"start_date":"2019-02-08","completion_date":"2024-07-09","last_update_date":"2026-09-21","source_url":"https://clinicaltrials.gov/study/NCT03994562","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-24T01:17:16.301579+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":"DELFAF","age_range":"65 Years","comparator":null,"organization":"Gérond'if","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["Assessment of the emotional, physical and financial burden on a caregiver according Zarit burden scale — Day 0","Measuring cognitive impairment according Mini-Mental State Examination (MMSE) scores — Day 0","Screening for a nutritional disorder according Body Mass Index (BMI) score — Day 0","Assessment of verbal episodic memory according Grober and Buschke's test — Day 0","Screening of the undernutrition according mini nutritional assessment (MNA) — Day 0","Assessment of anxiety according Goldberg scale — Day 0","Assessment of humor in geriatrics according Geriatric Depression Scale (GDS) — Day 0"],"design_description":null,"source_has_results":false},"controlled_terms":["Fragility"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct03994562","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2019-02-08 to 2024-07-09","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.381Z","intervention":[],"participants":120,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Assessment of the emotional, physical and financial burden on a caregiver according Zarit burden scale — Day 0","Measuring cognitive impairment according Mini-Mental State Examination (MMSE) scores — Day 0","Screening for a nutritional disorder according Body Mass Index (BMI) score — Day 0","Assessment of verbal episodic memory according Grober and Buschke's test — Day 0","Screening of the undernutrition according mini nutritional assessment (MNA) — Day 0","Assessment of anxiety according Goldberg scale — Day 0","Assessment of humor in geriatrics according Geriatric Depression Scale (GDS) — Day 0"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/22142","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}