{"type":"trials","record":{"id":22155,"source_id":"clinicaltrials-gov","external_id":"NCT07633483","title":"The Relationship Between Preoperative Anxiety Level and Frailty Score in Elderly Patients Scheduled for Elective Hip Arthroplasty: A Prospective Observational Study","brief_summary":"Frailty is a state of vulnerability resulting from decreased physiological reserve across multiple organ systems, impairing an individual's ability to withstand stressors. As the elderly population grows worldwide, the proportion of older adults undergoing surgical procedures continues to rise, and frailty is expected to become increasingly prevalent among surgical candidates. Anxiety is one of the most common psychiatric conditions, affecting approximately one in three individuals globally. Preoperative anxiety may negatively influence surgical outcomes, particularly in older and more vulnerable patients. This prospective observational study aims to evaluate the relationship between preoperative anxiety level and frailty score in elderly patients aged 65 years and older scheduled for elective hip arthroplasty. Frailty will be assessed using the FRAIL Scale (Fatigue, Resistance, Ambulation, Illness, Loss of Weight), and anxiety will be measured using the Hamilton Anxiety Rating Scale (HAM-A). Secondary outcomes include the prevalence of frailty and anxiety, the effect of frailty on length of hospital stay, postoperative intensive care unit admission rates, and the relationship between frailty and preoperative laboratory and hemodynamic parameters.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Başakşehir Çam & Sakura City Hospital","enrollment":142,"countries":["Turkey (Türkiye)"],"start_date":"2024-12-01","completion_date":"2026-07-01","last_update_date":"2026-09-16","source_url":"https://clinicaltrials.gov/study/NCT07633483","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-24T01:17:16.301579+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":null,"organization":"Başakşehir Çam & Sakura City Hospital","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["Association Between Frailty Score and Preoperative Anxiety Level — 24 hours before surgery","Prevalence of Frailty — 24 hours before surgery","Prevalence of Preoperative Anxiety — 24 hours before surgery","Correlation Between Frailty Score and Length of Hospital Stay — From hospital admission to discharge, assessed up to 2…","Correlation Between Preoperative Anxiety Level and Length of Hospital Stay — From surgery to discharge, assessed up to…","Correlation Between Frailty Score and Postoperative ICU Admission Rate — From hospital admission to discharge, assessed…","Correlation Between Preoperative Anxiety Level and Postoperative ICU Admission Rate — From surgery to discharge, assess…","Correlation Between Frailty Score and In-Hospital Mortality Rate — From hospital admission to discharge, assessed up to…","Correlation Between Preoperative Anxiety Level and In-Hospital Mortality Rate — From hospital admission to discharge, a…","Association Between Frailty Score and Sociodemographic Characteristics — 24 hours before surgery","Association Between Preoperative Anxiety Level and Sociodemographic Characteristics — 24 hours before surgery","Correlation Between Frailty Score and Preoperative Laboratory Parameters — At hospital admission","Correlation Between Preoperative Anxiety Level and Preoperative Laboratory Parameters — At hospital admission"],"design_description":null,"source_has_results":false},"controlled_terms":["Fraility","Anxiety, Preoperative","Hip Arthroplasty"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct07633483","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-12-01 to 2026-07-01","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.384Z","intervention":[],"participants":142,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Association Between Frailty Score and Preoperative Anxiety Level — 24 hours before surgery","Prevalence of Frailty — 24 hours before surgery","Prevalence of Preoperative Anxiety — 24 hours before surgery","Correlation Between Frailty Score and Length of Hospital Stay — From hospital admission to discharge, assessed up to 2…","Correlation Between Preoperative Anxiety Level and Length of Hospital Stay — From surgery to discharge, assessed up to…","Correlation Between Frailty Score and Postoperative ICU Admission Rate — From hospital admission to discharge, assessed…","Correlation Between Preoperative Anxiety Level and Postoperative ICU Admission Rate — From surgery to discharge, assess…","Correlation Between Frailty Score and In-Hospital Mortality Rate — From hospital admission to discharge, assessed up to…","Correlation Between Preoperative Anxiety Level and In-Hospital Mortality Rate — From hospital admission to discharge, a…","Association Between Frailty Score and Sociodemographic Characteristics — 24 hours before surgery","Association Between Preoperative Anxiety Level and Sociodemographic Characteristics — 24 hours before surgery","Correlation Between Frailty Score and Preoperative Laboratory Parameters — At hospital admission","Correlation Between Preoperative Anxiety Level and Preoperative Laboratory Parameters — At hospital admission"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/22155","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}