{"type":"trials","record":{"id":22203,"source_id":"clinicaltrials-gov","external_id":"NCT07345832","title":"The Effect of Volunteer-Engaged Lifestyle Optimisation Via ICOPE on Sarcopenia in Older Adults (VELO-S)","brief_summary":"Sarcopenia prevention and management are highly prioritised goals in the Healthy Ageing agenda. The study aims to: 1) evaluate the effects of the digital-enhanced, volunteer-engaged collaborative care pathway to improve sarcopenia, reduce fall risk, and increase health-related quality of life (HRQL) among community-dwelling older adults with risk of, or diagnosed with, sarcopenia; 2) evaluate whether the volunteers who received health coach capacity training and supported the intervention experienced health benefits across time; 3) explore the engagement experiences and perceived effects of elderly participants with sarcopenia during the program; 4) evaluate the intervention implementation process and effects from the perspectives of social care workers.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"The University of Hong Kong","enrollment":200,"countries":["Hong Kong"],"start_date":"2026-02-01","completion_date":"2027-09-30","last_update_date":"2026-09-08","source_url":"https://clinicaltrials.gov/study/NCT07345832","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-24T01:17:16.887272+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"60 Years","comparator":"Attention control","organization":"The University of Hong Kong","interventions":["Volunteer-Engaged Lifestyle Optimisation via ICOPE for Sarcopenia program (VELO-S)","Attention control"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Appendicular skeletal muscle mass index (ASMI) — Baseline (T0), 3 months (T1), and 6 months (T2)","Handgrip Strength — Baseline (T0), 3 months (T1), and 6 months (T2)","Short Physical Performance Battery (SPPB) — baseline (T0), 3 months (T1), and 3 months (T2)","Sarcopenia and calf circumference scale (SARC-CalF) — Baseline (T0), 3 months (T1), and 6 months (T2)","11-item Edmonton Frail Scale — Baseline (T0), 3 months (T1), and 6 months (T2)","Timed Up and Go (TUG) test — Baseline (T0), 3 months (T1), and 6 months (T2)","The Mini Nutritional Assessment (MNA) — Baseline (T0), 3 months (T1), and 6 months (T2)","International Physical Activity Questionnaire (IPAQ-Short) — Baseline (T0), 3 months (T1), and 6 months (T2)","The EuroQoL-5D-5L instruments — Baseline (T0), 3 months (T1), and 6 months (T2)","The EuroQoL-5D-5L Visual Analog Scale — Baseline (T0), 3 months (T1), and 6 months (T2)","Lipid Biomarkers — Baseline (T0)","Metabolic Biomarkers — Baseline (T0)"],"design_description":"RANDOMIZED · PARALLEL · PREVENTION · SINGLE","source_has_results":false},"controlled_terms":["Sarcopenia","Sarcopenia in Elderly","Fall Prevention in Healthy Aging","Frailty Syndrome","Malnutrition Elderly","Frailty","Volunteer-Engaged Lifestyle Optimisation via ICOPE for Sarcopenia program (VELO-S)","Attention control"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07345832","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-02-01 to 2027-09-30","comparator":"Attention control","confidence":"structured-source","population":"ALL · 60 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.755Z","intervention":["Volunteer-Engaged Lifestyle Optimisation via ICOPE for Sarcopenia program (VELO-S)","Attention control"],"participants":200,"study_design":"RANDOMIZED · PARALLEL · PREVENTION · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Appendicular skeletal muscle mass index (ASMI) — Baseline (T0), 3 months (T1), and 6 months (T2)","Handgrip Strength — Baseline (T0), 3 months (T1), and 6 months (T2)","Short Physical Performance Battery (SPPB) — baseline (T0), 3 months (T1), and 3 months (T2)","Sarcopenia and calf circumference scale (SARC-CalF) — Baseline (T0), 3 months (T1), and 6 months (T2)","11-item Edmonton Frail Scale — Baseline (T0), 3 months (T1), and 6 months (T2)","Timed Up and Go (TUG) test — Baseline (T0), 3 months (T1), and 6 months (T2)","The Mini Nutritional Assessment (MNA) — Baseline (T0), 3 months (T1), and 6 months (T2)","International Physical Activity Questionnaire (IPAQ-Short) — Baseline (T0), 3 months (T1), and 6 months (T2)","The EuroQoL-5D-5L instruments — Baseline (T0), 3 months (T1), and 6 months (T2)","The EuroQoL-5D-5L Visual Analog Scale — Baseline (T0), 3 months (T1), and 6 months (T2)","Lipid Biomarkers — Baseline (T0)","Metabolic Biomarkers — Baseline (T0)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/22203","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}