{"type":"trials","record":{"id":22442,"source_id":"clinicaltrials-gov","external_id":"NCT06495437","title":"Preliminary Safety and Efficacy Study of Extracellular Vesicle Infusion in the Intervention of Age-related Phenotypes With Impaired Glucose Tolerance.","brief_summary":"The objective of this exploratory study was to evaluate the initial safety of human mesenchymal stem cell-derived extracellular vesicle infusion in an age-related phenotype with impaired glucose tolerance","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"BEAUTECH","enrollment":20,"countries":[],"start_date":"2024-08-01","completion_date":"2026-12-31","last_update_date":"2024-07-19","source_url":"https://clinicaltrials.gov/study/NCT06495437","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-24T01:17:19.146275+00:00","last_seen_at":"2026-09-25T06:05:36.473+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"35 Years to 65 Years","comparator":null,"organization":"BEAUTECH","interventions":["Intravenous infusion of extracellular vesicle preparation derived from Wharton's jelly mesenchymal stem cells."],"registry_source":"ClinicalTrials.gov","outcome_measures":["safety evaluation — 0-12 weeks","Effectiveness evaluation — 0-12 weeks"],"design_description":"NA · SINGLE GROUP · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Impaired Glucose Tolerance","Intravenous infusion of extracellular vesicle preparation derived from Wharton's jelly mesenchymal stem cells."],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: extracellular vesicle.","quality_checked_at":"2026-09-25T06:05:36.864987+00:00","duplicate_cluster_key":"id:nct06495437","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-08-01 to 2026-12-31","comparator":null,"confidence":"structured-source","population":"ALL · 35 Years to 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:05:36.477Z","intervention":["Intravenous infusion of extracellular vesicle preparation derived from Wharton's jelly mesenchymal stem cells."],"participants":20,"study_design":"NA · SINGLE GROUP · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["safety evaluation — 0-12 weeks","Effectiveness evaluation — 0-12 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"intercellular-communication","is_published":true,"match_reasons":["Title contains controlled term: extracellular vesicle.","Abstract contains controlled term: extracellular vesicle.","Source terminology contains: extracellular vesicle.","Title supplies longevity context: age-related.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Intercellular communication","slug":"intercellular-communication"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/22442","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}