{"type":"trials","record":{"id":22587,"source_id":"clinicaltrials-gov","external_id":"NCT00497978","title":"The Effect of Taurine on Morbidity and Mortality in the Elderly Hip Fracture Patient","brief_summary":"The purpose of this study is to reduce the postoperative morbidity and mortality in the elderly hip fracture patient, by giving them taurine peri-operatively.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Medical Center Alkmaar","enrollment":236,"countries":["Netherlands"],"start_date":"2008-03-01","completion_date":"2011-10-01","last_update_date":"2011-12-30","source_url":"https://clinicaltrials.gov/study/NCT00497978","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-24T02:17:04.2999+00:00","last_seen_at":"2026-09-25T06:15:54.38+00:00","metadata":{"sex":"ALL","acronym":"TAUP","age_range":"75 Years","comparator":"1; 2","organization":"Medical Center Alkmaar","interventions":["taurine","placebo"],"registry_source":"ClinicalTrials.gov","outcome_measures":["morbidity and mortality — 1 year","antioxidant/oxidant parameters and inflammatory mediators — 1 week","postoperative insulin resistance — 1 week","mitochondrial dysfunction in the skeletal muscle — 1 week","postoperative delirium incidence, duration and severity — 1 week"],"design_description":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · TRIPLE","source_has_results":false},"controlled_terms":["Insulin Resistance","Elderly Patient","Oxidative Stress","taurine","placebo"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":35,"publication_state":"published","match_explanation":"Title contains controlled term: taurine.","quality_checked_at":"2026-09-25T06:16:07.48358+00:00","duplicate_cluster_key":"id:nct00497978","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2008-03-01 to 2011-10-01","comparator":"1; 2","confidence":"structured-source","population":"ALL · 75 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:15:54.508Z","intervention":["taurine","placebo"],"participants":236,"study_design":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · TRIPLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["morbidity and mortality — 1 year","antioxidant/oxidant parameters and inflammatory mediators — 1 week","postoperative insulin resistance — 1 week","mitochondrial dysfunction in the skeletal muscle — 1 week","postoperative delirium incidence, duration and severity — 1 week"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"taurine","is_published":true,"match_reasons":["Title contains controlled term: taurine.","Abstract contains controlled term: taurine.","Source terminology contains: taurine.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Taurine","slug":"taurine"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/22587","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}