{"type":"trials","record":{"id":22629,"source_id":"clinicaltrials-gov","external_id":"NCT07292272","title":"Halt Aging in Survivors of Blood Cancers","brief_summary":"Older survivors of blood cancer are at a high risk of accelerated biological aging, which increases their risk of developing multiple aging-related conditions. Whereas physical exercise can improve overall health, older cancer survivors do not meet the recommended physical activity, highlighting the need to develop behavioral interventions to increase adherence. Several other knowledge gaps exist to implement exercise interventions in older survivors of blood cancer; the dose and duration of exercise necessary to slow biological aging in older blood cancer survivors remain unknown. To bridge these gaps in knowledge, we have designed a Phase 2 randomized control trial to test the effects of behavioral and exercise interventions on various outcomes.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University of Nebraska","enrollment":180,"countries":["United States"],"start_date":"2026-04-09","completion_date":"2033-03-25","last_update_date":"2026-07-01","source_url":"https://clinicaltrials.gov/study/NCT07292272","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-24T03:17:02.721888+00:00","last_seen_at":"2026-09-25T07:05:20.248+00:00","metadata":{"sex":"ALL","acronym":"HALTAging-1","age_range":"50 Years","comparator":"Enhanced Usual Care-Virtual Gym","organization":"University of Nebraska","interventions":["Behavioral Coaching Intervention","Virtual Exercise Platform"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Percentage of participants who adhered to the exercise regimen at 6-months post enrollment. — 6 Months from start of pr…","Percentage of participants who adhered to the exercise regimen at 12-months post enrollment. — 12 Months from start of…","Physical Function (6- Minute Walk Test Distance) — 6 months from randomization"],"design_description":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · NONE","source_has_results":false},"controlled_terms":["Hematological Malignancy","Leukemia","Lymphoid Leukemia","Multiple Myeloma","Myeloid Leukemia","Monocytic Leukemia","Non-hodgkin Lymphoma","Other Hematologic Condition","Behavioral Coaching Intervention","Virtual Exercise Platform"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: cancer.","quality_checked_at":"2026-09-25T07:05:30.295959+00:00","duplicate_cluster_key":"id:nct07292272","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-04-09 to 2033-03-25","comparator":"Enhanced Usual Care-Virtual Gym","confidence":"structured-source","population":"ALL · 50 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T07:05:20.264Z","intervention":["Behavioral Coaching Intervention","Virtual Exercise Platform"],"participants":180,"study_design":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Percentage of participants who adhered to the exercise regimen at 6-months post enrollment. — 6 Months from start of pr…","Percentage of participants who adhered to the exercise regimen at 12-months post enrollment. — 12 Months from start of…","Physical Function (6- Minute Walk Test Distance) — 6 months from randomization"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"cancer-and-aging","is_published":true,"match_reasons":["Title contains controlled term: cancer.","Abstract contains controlled term: cancer.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Cancer and ageing","slug":"cancer-and-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/22629","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}