{"type":"trials","record":{"id":228,"source_id":"clinicaltrials-gov","external_id":"NCT06040125","title":"Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial","brief_summary":"The purpose of this study is to determine whether a 16-week supervised, clinic-based circuit training intervention utilizing resistance and functional exercises and self-directed aerobic exercise will improve frailty and sarcopenic status and disease progression outcomes among pre-frail/frail metastatic prostate cancer patients receiving androgen deprivation therapy (ADT). The names of the study intervention involved in this study is: • Supervised circuit training (aerobic and resistance exercise regimen)","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Dana-Farber Cancer Institute","enrollment":80,"countries":["United States"],"start_date":"2024-01-01","completion_date":"2028-02-28","last_update_date":"2026-09-10","source_url":"https://clinicaltrials.gov/study/NCT06040125","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-14T02:45:01.392906+00:00","last_seen_at":"2026-09-15T00:18:33.921+00:00","metadata":{"acronym":null,"organization":"Dana-Farber Cancer Institute","source_has_results":false},"controlled_terms":[],"relevance_confidence":80,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Published automatically with 80% topic confidence after controlled-term evaluation.","quality_checked_at":"2026-09-15T02:15:56.576005+00:00","duplicate_cluster_key":"registry:nct06040125","duplicate_of_id":null,"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Legacy trial evaluated automatically against controlled title, summary, and longevity-context rules."],"matched_fields":["title"],"relevance_score":80,"intelligence_topics":{"name":"Exercise","slug":"exercise"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/228","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}