{"type":"trials","record":{"id":24562,"source_id":"clinicaltrials-gov","external_id":"NCT06851988","title":"Can Exercise Ameliorate Immunosenescence and Thereby Reduce Relapse in Head and Neck Cancer Patients","brief_summary":"Through the implementation of this three-year project, investigators expect to find a safe and effective exercise prescription for patients with oral cancer after surgery. The findings will encourage and promise and add further support to the concept that exercise prescription is worth implementation as part of care for the patients with head and neck cancer.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Chang Gung Memorial Hospital","enrollment":290,"countries":["Taiwan"],"start_date":"2023-05-03","completion_date":"2026-10-30","last_update_date":"2026-09-24","source_url":"https://clinicaltrials.gov/study/NCT06851988","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-24T13:17:06.158638+00:00","last_seen_at":"2026-09-25T06:15:06.064+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"20 Years to 80 Years","comparator":"Head and Neck patient after CCRT treatment-Experimental group; Head and Neck patient after CCRT treatment-Validation group","organization":"Chang Gung Memorial Hospital","interventions":["HIIT & Record of physical activities at home.","HIIT only"],"registry_source":"ClinicalTrials.gov","outcome_measures":["percent of participants with phenoage and age — baseline before CCRT","percent of participants with phenoage and age — 1 months after the completion of CCRT","percent of participants with phenoage and age — 6 months after the completion of CCRT","percent of participants with phenoage and age — 9 months after the completion of CCRT","Peak VO2 (ml/min/kg) of participants — baseline before CCRT","Peak VO2 (ml/min/kg) of participants — 1 months after the completion of CCRT","Peak VO2 (ml/min/kg) of participants — 6 months after the completion of CCRT","Peak VO2 (ml/min/kg) of participants — 9 months after the completion of CCRT","Questionnaire of European Organisation for Research and Treatment of Cancer Quality of Life Head and Neck Module (EORTC…"],"design_description":"RANDOMIZED · PARALLEL · OTHER · NONE","source_has_results":false},"controlled_terms":["Aging","High-intensity Interval Training","Head and Neck Cancers - Tonsils","HIIT & Record of physical activities at home.","HIIT only"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: cancer.","quality_checked_at":"2026-09-25T06:15:09.632521+00:00","duplicate_cluster_key":"id:nct06851988","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-05-03 to 2026-10-30","comparator":"Head and Neck patient after CCRT treatment-Experimental group; Head and Neck patient after CCRT treatment-Validation group","confidence":"structured-source","population":"ALL · 20 Years to 80 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:15:06.068Z","intervention":["HIIT & Record of physical activities at home.","HIIT only"],"participants":290,"study_design":"RANDOMIZED · PARALLEL · OTHER · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["percent of participants with phenoage and age — baseline before CCRT","percent of participants with phenoage and age — 1 months after the completion of CCRT","percent of participants with phenoage and age — 6 months after the completion of CCRT","percent of participants with phenoage and age — 9 months after the completion of CCRT","Peak VO2 (ml/min/kg) of participants — baseline before CCRT","Peak VO2 (ml/min/kg) of participants — 1 months after the completion of CCRT","Peak VO2 (ml/min/kg) of participants — 6 months after the completion of CCRT","Peak VO2 (ml/min/kg) of participants — 9 months after the completion of CCRT","Questionnaire of European Organisation for Research and Treatment of Cancer Quality of Life Head and Neck Module (EORTC…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"cancer-and-aging","is_published":true,"match_reasons":["Title contains controlled term: cancer.","Abstract contains controlled term: cancer.","Source terminology contains: cancer.","Title supplies longevity context: senescence.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Cancer and ageing","slug":"cancer-and-aging"}},{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise.","Abstract contains controlled term: exercise.","Title supplies longevity context: senescence.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}},{"topic_slug":"immune-aging","is_published":true,"match_reasons":["Title contains controlled term: immunosenescence.","Title supplies longevity context: senescence.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Immune ageing","slug":"immune-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/24562","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}