{"type":"trials","record":{"id":253,"source_id":"clinicaltrials-gov","external_id":"NCT07695961","title":"Early Time-Restricted Eating Combined With Exercise in Older Adults","brief_summary":"This randomized controlled trial aims to investigate the effects of Early Time-Restricted Eating (eTRE) combined with a multicomponent exercise program on bone health, physical function, and fall risk in healthy older adults. A total of approximately 44 healthy adults aged 60 years and older will be recruited and randomly assigned to one of two groups. The experimental group will follow an Early Time-Restricted Eating schedule combined with a structured multicomponent exercise program. The control group will not receive any dietary timing intervention or structured exercise program and will continue their usual daily lifestyle. The intervention will last for 6 months. Participants in the exercise program will perform supervised sessions including resistance training, balance exercises, aerobic activity, and flexibility exercises. The Early Time-Restricted Eating protocol will involve consuming all daily food intake within an early daytime window while maintaining usual dietary quality and adequate energy and nutrient intake. The main outcomes of the study include changes in bone mineral density, gait performance, balance, and fall risk. These outcomes will be measured at baseline and after the intervention period. This study will provide evidence on whether combining early time-restricted eating with structured exercise can improve musculoskeletal health and functional ability, and reduce fall risk in older adults.","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University of Manouba","enrollment":44,"countries":["Tunisia"],"start_date":"2026-06-15","completion_date":"2026-12-30","last_update_date":"2026-07-13","source_url":"https://clinicaltrials.gov/study/NCT07695961","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-14T02:45:01.944738+00:00","last_seen_at":"2026-09-25T06:25:43.79+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"60 Years to 85 Years","comparator":"Control","organization":"University of Manouba","interventions":["Early Time-Restricted Eating (eTRE)+Exercise Intervention"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Bone Mineral Density (BMD) — Baseline and 6 months (pre-intervention and post-intervention)","Gait performance — Baseline and 6 months (pre-intervention and post-intervention)","Balance — Baseline and 6 months (pre-intervention and post-intervention)","Fall Risk — Baseline and 6 months (pre-intervention and post-intervention)"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Nutrition","Health and Wellbeing","Aging","Time Restricted Eating","Bone Health","Early Time-Restricted Eating (eTRE)+Exercise Intervention"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: time-restricted eating.","quality_checked_at":"2026-09-25T06:25:44.537089+00:00","duplicate_cluster_key":"id:nct07695961","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-06-15 to 2026-12-30","comparator":"Control","confidence":"structured-source","population":"ALL · 60 Years to 85 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:43.794Z","intervention":["Early Time-Restricted Eating (eTRE)+Exercise Intervention"],"participants":44,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Bone Mineral Density (BMD) — Baseline and 6 months (pre-intervention and post-intervention)","Gait performance — Baseline and 6 months (pre-intervention and post-intervention)","Balance — Baseline and 6 months (pre-intervention and post-intervention)","Fall Risk — Baseline and 6 months (pre-intervention and post-intervention)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"caloric-restriction","is_published":true,"match_reasons":["Title contains controlled term: time-restricted eating.","Abstract contains controlled term: time-restricted eating.","Source terminology contains: time-restricted eating.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Caloric restriction","slug":"caloric-restriction"}},{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise.","Abstract contains controlled term: exercise.","Source terminology contains: exercise.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}},{"topic_slug":"time-restricted-eating","is_published":true,"match_reasons":["Title contains controlled term: time-restricted eating, early time-restricted.","Abstract contains controlled term: time-restricted eating, early time-restricted.","Source terminology contains: time-restricted eating, early time-restricted.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Time-restricted eating","slug":"time-restricted-eating"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/253","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}