{"type":"trials","record":{"id":28352,"source_id":"clinicaltrials-gov","external_id":"NCT06354010","title":"Cross-sectional and Prospective Study to Characterize Early-onset Presbycusis","brief_summary":"The purpose of this study is to characterize and assess the evolution of hearing impairment of patients with adulthood-onset bilateral sensorineural hearing loss carrying mutations on GJB2 gene.","overall_status":"Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Sensorion","enrollment":100,"countries":["United States","France"],"start_date":"2024-06-14","completion_date":"2027-07-01","last_update_date":"2026-05-08","source_url":"https://clinicaltrials.gov/study/NCT06354010","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T00:17:13.50034+00:00","last_seen_at":"2026-09-25T06:25:04.647+00:00","metadata":{"sex":"ALL","acronym":"SONG","age_range":"30 Years to 55 Years","comparator":null,"organization":"Sensorion","interventions":["Genotyping","Audiological assessments"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Evolution of hearing impairment of adult patients with early-onset presbycusis carrying mutations in GJB2 gene. — 2 yea…","Evolution of hearing impairment of adult patients with early-onset presbycusis carrying mutations in GJB2 gene — 2 years","Genetic characteristics of adult patients with early-onset presbycusis — Unique visit","Audiological characteristics of adult patients with early-onset presbycusis — Unique visit","Mood evaluation in adult patients with early-onset presbycusis carrying mutations in GJB2 gene — 2 years"],"design_description":null,"source_has_results":false},"controlled_terms":["Sensorineural Hearing Loss, Bilateral","Genotyping","Audiological assessments"],"relevance_confidence":60,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: presbycusis.","quality_checked_at":"2026-09-25T06:25:07.732232+00:00","duplicate_cluster_key":"id:nct06354010","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-06-14 to 2027-07-01","comparator":null,"confidence":"structured-source","population":"ALL · 30 Years to 55 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:04.654Z","intervention":["Genotyping","Audiological assessments"],"participants":100,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Evolution of hearing impairment of adult patients with early-onset presbycusis carrying mutations in GJB2 gene. — 2 yea…","Evolution of hearing impairment of adult patients with early-onset presbycusis carrying mutations in GJB2 gene — 2 years","Genetic characteristics of adult patients with early-onset presbycusis — Unique visit","Audiological characteristics of adult patients with early-onset presbycusis — Unique visit","Mood evaluation in adult patients with early-onset presbycusis carrying mutations in GJB2 gene — 2 years"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"hearing-aging","is_published":true,"match_reasons":["Title contains controlled term: presbycusis.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","study type"],"relevance_score":60,"intelligence_topics":{"name":"Hearing ageing","slug":"hearing-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/28352","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}