{"type":"trials","record":{"id":28361,"source_id":"clinicaltrials-gov","external_id":"NCT00488007","title":"Clinical Trial on Alzheimer Disease, Presbycusis and Hearing Aids","brief_summary":"This is a 12-months' randomized clinical trial that aims at studying the benefit of bilateral hearing aids in hearing impaired patients suffering from a slight to moderate stage Alzheimer disease. The benefit of this intervention will be studied in the cognitive, behavioural, quality of life and economic fields. 2groups are involved in this trial: Intervention group: 12 months' treatment with active hearing aids, fitted hearing impairment Control group: 6 months' treatment with placebo hearing aids, followed with 6 months' active hearing aids, fitted hearing impairment","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Hospices Civils de Lyon","enrollment":51,"countries":["France"],"start_date":"2007-05-01","completion_date":"2013-09-01","last_update_date":"2025-12-19","source_url":"https://clinicaltrials.gov/study/NCT00488007","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T00:17:13.50034+00:00","last_seen_at":"2026-09-25T06:25:04.647+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":"Inactive Hearing aids","organization":"Hospices Civils de Lyon","interventions":["Hearing aids used : PHONAK Savia and Valeo"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Cognitive benefit evaluated thanks to the ADAS-Cog scale — Times of measurements: 0, 6th and 12th month","Cognitive scales: MMSE, Grober and Buschke, Digit symbol test — 0, 6th and 12th month","Behavioural scales: IADL, NPI — 1st week, 3rd 6th 9th and 12th month","Quality of life scales: Zarit scale and ADRQL — Zarit scale(every 2 months during the study time), ADRQL (0, 6th and 12…","Consumption questionnaire — monthly"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · DOUBLE","source_has_results":false},"controlled_terms":["Alzheimer Disease","Presbycusis","Hearing aids used : PHONAK Savia and Valeo"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: presbycusis.","quality_checked_at":"2026-09-25T06:25:07.732232+00:00","duplicate_cluster_key":"id:nct00488007","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2007-05-01 to 2013-09-01","comparator":"Inactive Hearing aids","confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:04.657Z","intervention":["Hearing aids used : PHONAK Savia and Valeo"],"participants":51,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · DOUBLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Cognitive benefit evaluated thanks to the ADAS-Cog scale — Times of measurements: 0, 6th and 12th month","Cognitive scales: MMSE, Grober and Buschke, Digit symbol test — 0, 6th and 12th month","Behavioural scales: IADL, NPI — 1st week, 3rd 6th 9th and 12th month","Quality of life scales: Zarit scale and ADRQL — Zarit scale(every 2 months during the study time), ADRQL (0, 6th and 12…","Consumption questionnaire — monthly"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"hearing-aging","is_published":true,"match_reasons":["Title contains controlled term: presbycusis.","Source terminology contains: presbycusis.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","controlled terminology","study type"],"relevance_score":100,"intelligence_topics":{"name":"Hearing ageing","slug":"hearing-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/28361","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}