{"type":"trials","record":{"id":28520,"source_id":"clinicaltrials-gov","external_id":"NCT06879639","title":"Exercise Impact in Elderly With Multimorbidity: HbA1c and Blood Pressure","brief_summary":"The main objective of the study is to compare the effect of two different types of physical exercise modalities on glycated hemoglobin and blood pressure in elderly individuals with multimorbidity. The main characteristic of the proposal is that it is experimental, with two intervention groups with physical exercise that will be randomized in the order of participation of the groups and forwarded to the researchers regarding the evaluations and training periods. In addition, the study will be controlled, as it has a control group that will not perform any intervention with physical exercises during the study period. To allocate the participants in each exercise group and for the control group, the researchers will use the 1:1 method, the user will receive an automatic generator through the random.org website. The main questions raised by the studies will be: Is land-based training more effective than aquatic training for this population in improving the primary outcomes? Is there a difference between training at these intensities and not doing any physical exercise in this population with these primary outcomes? Participants in the 2 intervention groups will: Train 3x per week for 10 weeks at intensities that will progress over the weeks.","overall_status":"Active Not Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Universidade do Porto","enrollment":63,"countries":["Portugal"],"start_date":"2024-09-09","completion_date":"2026-12-31","last_update_date":"2026-05-27","source_url":"https://clinicaltrials.gov/study/NCT06879639","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T00:17:15.048652+00:00","last_seen_at":"2026-09-25T07:05:20.248+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"60 Years","comparator":null,"organization":"Universidade do Porto","interventions":["Exercise","Control"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Glycated hemoglobin (Hb1Ac) — 10 weeks","Blood pressure — 10 weeks","Heart rate variability — 10 weeks","Lipid Profile (LDL, HDL, VLDL and Triglycerides) — 10 weeks","Body Mass Index (BMI) — 10 weeks","Fasting glucose — 10 weeks","Agility — 10 weeks","Cardiorespiratory fitness — 10 weeks","Hand grip strength — 10 weeks","Sit and stand test — 10 weeks","World Health Organization Quality of Life - WHOQOL questionnaire — 10 weeks","Internation Physical Activity - IPAQ questionnaire — 10 weeks","Pittsburgh Sleep Quality Index - PSQIquestionnaire — 10 weeks","Depression, Anxiety, and Stress Scale - DASS 21 — 10 weeks","Balance test — 10 weeks","Muscle electrical activity — 10 weeks"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Hypertension","Diabetes","Osteoarthritis","Depression Disorders","Multimorbidity","Respiratory Disorders","Sarcopenia in Elderly","Dyslipidemia","High Blood Cholesterol","Obese Patients","Exercise","Control"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: multimorbidity.","quality_checked_at":"2026-09-25T07:05:30.295959+00:00","duplicate_cluster_key":"id:nct06879639","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-09-09 to 2026-12-31","comparator":null,"confidence":"structured-source","population":"ALL · 60 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T07:05:20.269Z","intervention":["Exercise","Control"],"participants":63,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Glycated hemoglobin (Hb1Ac) — 10 weeks","Blood pressure — 10 weeks","Heart rate variability — 10 weeks","Lipid Profile (LDL, HDL, VLDL and Triglycerides) — 10 weeks","Body Mass Index (BMI) — 10 weeks","Fasting glucose — 10 weeks","Agility — 10 weeks","Cardiorespiratory fitness — 10 weeks","Hand grip strength — 10 weeks","Sit and stand test — 10 weeks","World Health Organization Quality of Life - WHOQOL questionnaire — 10 weeks","Internation Physical Activity - IPAQ questionnaire — 10 weeks","Pittsburgh Sleep Quality Index - PSQIquestionnaire — 10 weeks","Depression, Anxiety, and Stress Scale - DASS 21 — 10 weeks","Balance test — 10 weeks","Muscle electrical activity — 10 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"multimorbidity","is_published":true,"match_reasons":["Title contains controlled term: multimorbidity.","Abstract contains controlled term: multimorbidity.","Source terminology contains: multimorbidity.","Title supplies longevity context: elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Multimorbidity","slug":"multimorbidity"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/28520","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}