{"type":"trials","record":{"id":28583,"source_id":"clinicaltrials-gov","external_id":"NCT07567976","title":"Tai Chi Intervention for Balance Function in Older Adults: Predictive and Modifying Roles of Circadian Age","brief_summary":"This study investigates the effects of a 12-week Tai Chi intervention on balance function in community-dwelling older adults. Participants are randomly assigned to either a Tai Chi exercise group or a health education control group. The primary outcome is balance function measured by the Berg Balance Scale. Secondary outcomes include physical function, psychological well-being, cognitive function, and sleep quality. The study also explores the predictive and modifying roles of baseline circadian age on intervention outcomes.","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Zhide Liang","enrollment":90,"countries":[],"start_date":"2026-06-01","completion_date":"2027-03-01","last_update_date":"2026-07-02","source_url":"https://clinicaltrials.gov/study/NCT07567976","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T00:17:15.763923+00:00","last_seen_at":"2026-09-25T06:25:39.067+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"55 Years","comparator":"Health Education Control Group","organization":"Hainan Medical College","interventions":["Tai Chi Exercise","Health Education"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in Berg Balance Scale (BBS) Score — Change from baseline to end of intervention, up to 12 weeks","Change in Timed Up and Go (TUG) Test — Change from baseline to end of intervention, up to 12 weeks","Change in Grip Strength — Change from baseline to end of intervention, up to 12 weeks","Change in Balance Performance Measured by InBody Balance Trainer — Change from baseline to end of intervention, up to 1…","Change in Single-Leg Eye-Closed Standing Time — Change from baseline to end of intervention, up to 12 weeks","Change in Vertical Jump Height — Change from baseline to end of intervention, up to 12 weeks","Change in Reaction Time — Change from baseline to end of intervention, up to 12 weeks","Change in Activities-Specific Balance Confidence (ABC) Scale — Change from baseline to end of intervention, up to 12 we…","Change in Geriatric Depression Scale (GDS-15) Score — Change from baseline to end of intervention, up to 12 weeks","Change in Generalized Anxiety Disorder Scale (GAD-7) Score — Change from baseline to end of intervention, up to 12 weeks","Change in Shape Trail Test (STT) Part A and Part B Completion Time — Change from baseline to end of intervention, up to…","Change in Pittsburgh Sleep Quality Index (PSQI) Score — Change from baseline to end of intervention, up to 12 weeks"],"design_description":"RANDOMIZED · PARALLEL · PREVENTION · SINGLE","source_has_results":false},"controlled_terms":["Aging","Postural Balance","Accidental Falls","Tai Chi Exercise","Health Education"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: circadian.","quality_checked_at":"2026-09-25T06:25:42.287439+00:00","duplicate_cluster_key":"id:nct07567976","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-06-01 to 2027-03-01","comparator":"Health Education Control Group","confidence":"structured-source","population":"ALL · 55 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:39.081Z","intervention":["Tai Chi Exercise","Health Education"],"participants":90,"study_design":"RANDOMIZED · PARALLEL · PREVENTION · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in Berg Balance Scale (BBS) Score — Change from baseline to end of intervention, up to 12 weeks","Change in Timed Up and Go (TUG) Test — Change from baseline to end of intervention, up to 12 weeks","Change in Grip Strength — Change from baseline to end of intervention, up to 12 weeks","Change in Balance Performance Measured by InBody Balance Trainer — Change from baseline to end of intervention, up to 1…","Change in Single-Leg Eye-Closed Standing Time — Change from baseline to end of intervention, up to 12 weeks","Change in Vertical Jump Height — Change from baseline to end of intervention, up to 12 weeks","Change in Reaction Time — Change from baseline to end of intervention, up to 12 weeks","Change in Activities-Specific Balance Confidence (ABC) Scale — Change from baseline to end of intervention, up to 12 we…","Change in Geriatric Depression Scale (GDS-15) Score — Change from baseline to end of intervention, up to 12 weeks","Change in Generalized Anxiety Disorder Scale (GAD-7) Score — Change from baseline to end of intervention, up to 12 weeks","Change in Shape Trail Test (STT) Part A and Part B Completion Time — Change from baseline to end of intervention, up to…","Change in Pittsburgh Sleep Quality Index (PSQI) Score — Change from baseline to end of intervention, up to 12 weeks"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sleep","is_published":true,"match_reasons":["Title contains controlled term: circadian.","Abstract contains controlled term: sleep, circadian.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sleep","slug":"sleep"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/28583","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}