{"type":"trials","record":{"id":28692,"source_id":"clinicaltrials-gov","external_id":"NCT07637890","title":"Designing a Multicomponent Intervention for Improving Frailty. A Pilot Study in the Basque Country","brief_summary":"This pilot study tested whether a new program for older adults with frailty could realistically be carried out in primary health care. That is why the main objective of this study was to evaluate the viability and feasibility of the newly designed frailty intervention. People over 65 were recruited in two health centers and invited to join a 3 month program combining group exercise, a medication review by a pharmacist, and nutrition workshops. The study also collected information on mobility, strength, nutrition, mood, cognition, and quality of life. Most measures were taken at the start and again four and eight months later. The results will help refine the program and guide the design of a larger clinical trial.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Biogipuzkoa Health Research Institute","enrollment":32,"countries":["Spain"],"start_date":"2024-12-23","completion_date":"2025-09-25","last_update_date":"2026-06-12","source_url":"https://clinicaltrials.gov/study/NCT07637890","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T00:17:16.633874+00:00","last_seen_at":"2026-09-25T06:25:45.678+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":null,"organization":"Biogipuzkoa Health Research Institute","interventions":["Multi-component intervention: physical exercise, polypharmacy review and nutritional care"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Recruitment rates — Baseline","Time required to recruit the sample — Baseline","Participants evaluation time — From baseline to 8 months","Professionals' opinion on the difficulty and adequacy of the process — From baseline to 8 months","Adherence to the intervention — From baseline to 4 months","Participant satisfaction — Month 4","Change from Baseline in Functional Capacity at 4 and 8 months — From baseline to 8 months","Change from Baseline in Physical Activity at 4 and 8 months — From baseline to 8 months","Change from Baseline in Handgrip Strength at 4 and 8 months — From baseline to 8 months","Change from Baseline in Eating Habits at 4 and 8 months — From baseline to 8 months","Change from Baseline in Nutritional Status at 4 and 8 months — From Baseline to 8 months","Change from Baseline in Blood tests at 4 months — Frome baseline to 4 months","Change from Baseline in Pharmacological treatments at 4 months — From Baseline to 4 months","Change from Baseline in the Health-related quality of life at 4 and 8 months — From baseline to 8 months","Change from Baseline in Cognitive Status at 4 and 8 months — From baseline to 8 months","Change from Baseline in Anxiety and Depression Status at 4 and 8 months — From baseline to 8 months","Change from Baseline in Dependence at 4 and 8 months — From Baseline to 8 months","Change from Baseline in Social Connectedness at 4 and 8 months — From baseline to 8 months"],"design_description":"NA · SINGLE GROUP · OTHER · NONE","source_has_results":false},"controlled_terms":["Frailty","Multi-component intervention: physical exercise, polypharmacy review and nutritional care"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:25:48.368501+00:00","duplicate_cluster_key":"id:nct07637890","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-12-23 to 2025-09-25","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:45.687Z","intervention":["Multi-component intervention: physical exercise, polypharmacy review and nutritional care"],"participants":32,"study_design":"NA · SINGLE GROUP · OTHER · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Recruitment rates — Baseline","Time required to recruit the sample — Baseline","Participants evaluation time — From baseline to 8 months","Professionals' opinion on the difficulty and adequacy of the process — From baseline to 8 months","Adherence to the intervention — From baseline to 4 months","Participant satisfaction — Month 4","Change from Baseline in Functional Capacity at 4 and 8 months — From baseline to 8 months","Change from Baseline in Physical Activity at 4 and 8 months — From baseline to 8 months","Change from Baseline in Handgrip Strength at 4 and 8 months — From baseline to 8 months","Change from Baseline in Eating Habits at 4 and 8 months — From baseline to 8 months","Change from Baseline in Nutritional Status at 4 and 8 months — From Baseline to 8 months","Change from Baseline in Blood tests at 4 months — Frome baseline to 4 months","Change from Baseline in Pharmacological treatments at 4 months — From Baseline to 4 months","Change from Baseline in the Health-related quality of life at 4 and 8 months — From baseline to 8 months","Change from Baseline in Cognitive Status at 4 and 8 months — From baseline to 8 months","Change from Baseline in Anxiety and Depression Status at 4 and 8 months — From baseline to 8 months","Change from Baseline in Dependence at 4 and 8 months — From Baseline to 8 months","Change from Baseline in Social Connectedness at 4 and 8 months — From baseline to 8 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/28692","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}