{"type":"trials","record":{"id":28832,"source_id":"clinicaltrials-gov","external_id":"NCT07809763","title":"Wireless Wearable Home Prehabilitation for Older Adults With NSCLC","brief_summary":"This randomized controlled trial evaluates the efficacy and safety of a home-based prehabilitation program using wireless wearable monitoring devices in older patients (aged 65-85 years) with non-small cell lung cancer scheduled for curative lung resection. Participants are randomized 1:1 to either the intervention group, receiving a personalized exercise regimen (aerobic, resistance, and inspiratory muscle training) with continuous remote monitoring of steps, heart rate, and SpO₂ from 2-4 weeks preoperatively through 90 days postoperatively, or the control group receiving standard perioperative care. The primary endpoint is the between-group difference in FEV₁% predicted at 90 days post-surgery, adjusted for baseline. Secondary endpoints include functional capacity (6-minute walk distance), daily physical activity, hypoxemic burden (time with SpO₂\\<90%, nocturnal oxygen desaturation index), patient-reported outcomes (EORTC QLQ-C30/LC13, mMRC), postoperative complications, readmission rates, days alive and at home, and safety outcomes. The target sample size is 198 participants enrolled at West China Hospital of Sichuan University. Anticipated risks include exercise-related musculoskeletal strain, fatigue, and transient cardiopulmonary symptoms, as well as mild skin reactions from devices, all managed through individualized exercise prescriptions, remote safety thresholds, and a graded response protocol.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"West China Hospital","enrollment":196,"countries":["China"],"start_date":"2026-09-10","completion_date":"2028-07-31","last_update_date":"2026-09-09","source_url":"https://clinicaltrials.gov/study/NCT07809763","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T00:17:17.907301+00:00","last_seen_at":"2026-09-25T03:15:46.32+00:00","metadata":{"acronym":null,"organization":"West China Hospital","source_has_results":false},"controlled_terms":["Non-Small Cell Lung Cancer (NSCLC)","Rehabilitation","Thoracic Surgery","Prehabilitation","Digital Home-Based Prehabilitation","Standard Perioperative Care"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: wearable.","quality_checked_at":"2026-09-25T03:15:49.327669+00:00","duplicate_cluster_key":"id:nct07809763","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-09-10 to 2028-07-31","comparator":null,"confidence":"structured-source","population":null,"provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T03:37:00.711035+00:00","intervention":[],"participants":196,"study_design":"INTERVENTIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":[],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"digital-biomarkers","is_published":true,"match_reasons":["Title contains controlled term: wearable.","Abstract contains controlled term: wearable.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Digital biomarkers","slug":"digital-biomarkers"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/28832","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}