{"type":"trials","record":{"id":29196,"source_id":"clinicaltrials-gov","external_id":"NCT06953518","title":"An Open-Label Pilot Study of Qualia Senolytic Supplementation for the Attenuation of Systemic Inflammatory Cytokines","brief_summary":"This open-label pilot study includes adults aged 45 to 79 residing in the United States. The study will last 7 days. Participants will provide blood samples via an at-home finger-prick kit at baseline and day 7 and complete electronic surveys on health indicators at baseline, and days 3 and 7. All procedures are conducted remotely, with no in-person visits, to collect real-world evidence.","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Qualia Life Sciences","enrollment":40,"countries":["United States"],"start_date":"2025-05-12","completion_date":"2025-05-18","last_update_date":"2025-05-01","source_url":"https://clinicaltrials.gov/study/NCT06953518","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:08.862442+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"45 Years to 79 Years","comparator":"Qualia Senolytic","organization":"Qualia Life Sciences","interventions":["Qualia Senolytic"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Olink Target 48 Cytokine panel - TNF, IL1B, CXCL8, VEGFA — 1 week","Remaining biomarkers in the Olink Target 48 Cytokine panel — 1 week","36-Item Short Form Health Survey (SF-36) — 1 week","Frailty Index for Elders (FIFE) — 1 week","Depression Anxiety Stress Scale-21 (DASS-21) — 1 week","Aging Male/Female Symptom scale — 1 week","Side effect profile as measured by a custom Safety and Tolerability survey — 1 week"],"design_description":"NA · SINGLE GROUP · BASIC SCIENCE · NONE","source_has_results":false},"controlled_terms":["Inflammation","Qualia Senolytic"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: senolytic.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct06953518","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-05-12 to 2025-05-18","comparator":"Qualia Senolytic","confidence":"structured-source","population":"ALL · 45 Years to 79 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.513Z","intervention":["Qualia Senolytic"],"participants":40,"study_design":"NA · SINGLE GROUP · BASIC SCIENCE · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Olink Target 48 Cytokine panel - TNF, IL1B, CXCL8, VEGFA — 1 week","Remaining biomarkers in the Olink Target 48 Cytokine panel — 1 week","36-Item Short Form Health Survey (SF-36) — 1 week","Frailty Index for Elders (FIFE) — 1 week","Depression Anxiety Stress Scale-21 (DASS-21) — 1 week","Aging Male/Female Symptom scale — 1 week","Side effect profile as measured by a custom Safety and Tolerability survey — 1 week"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"senolytics","is_published":true,"match_reasons":["Title contains controlled term: senolytic.","Source terminology contains: senolytic.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","controlled terminology","study type"],"relevance_score":100,"intelligence_topics":{"name":"Senolytics","slug":"senolytics"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/29196","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}