{"type":"trials","record":{"id":29208,"source_id":"clinicaltrials-gov","external_id":"NCT06779032","title":"Clinical Profile of Skin Aging Based on Dermoscopy Photoaging Scale and Glogau Scale - Study of Leucocyte Telomere Length, Biomarker P16, and Body Mass Index","brief_summary":"To determine the relationship between clinical appearance, dermoscopic examination results of photoaging profiles based on clinical examination, DPAS score and leucocyte telomere length, to analyze the relationship between BMI, waist circumference, triglycerides, and cellular senescence biomarker p16 levels with a population experiencing skin aging and having Fitzpatrick III-V skin types. The questions which is aim to be answered are: 1. What is the photoaging profile based on clinical examination results in skin aging cases? 2. What is the photoaging profile based on DPAS scores in skin aging cases? 3. What is the leucocyte telomere length profile in skin aging cases? 4. What is the relationship between leucocyte telomere length and clinical examination in skin aging cases? 5. What is the relationship between leucocyte telomere length and DPAS degree in skin aging cases? 6. What is the profile of cellular senescence p16 biomarker levels in a population that has experienced clinical skin aging with Fitzpatrick III-V skin types? 7. What is the skin aging profile based on the Glogau and DPAS scales in a population with Fitzpatrick III-V skin types? 8. Is there a relationship between the results of the cellular senescence p16 biomarker examination and clinical skin aging assessed based on the Glogau and DPAS scales in a population with Fitzpatrick III-V skin types? 9. Is there a relationship between the results of BMI, waist circumference, and triglyceride examinations with clinical skin aging assessed using the Glogau and DPAS scales with Fitzpatrick III-V skin types?","overall_status":"Not Yet Recruiting","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Universitas Indonesia","enrollment":70,"countries":["Indonesia"],"start_date":"2025-02-05","completion_date":"2025-08-20","last_update_date":"2025-01-16","source_url":"https://clinicaltrials.gov/study/NCT06779032","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:08.862442+00:00","last_seen_at":"2026-09-25T06:20:14.553+00:00","metadata":{"sex":"ALL","acronym":"LTLP16","age_range":"31 Years to 61 Years","comparator":null,"organization":"Universitas Indonesia","interventions":["blood draw"],"registry_source":"ClinicalTrials.gov","outcome_measures":["profile of leucocyte telomere length — 1 year","profile of skin examination with dermoscopic photoaging scale (DPAS) — 1 year","Profile of body mass index — 1 year","profile of p16 — 1 year","profile of waist circumference — 1 year","profile triglycerides — 1 year"],"design_description":null,"source_has_results":false},"controlled_terms":["Aging Skin","Body Mass Index","Cellular Senescence","Triglycerides","Waist Circumference","blood draw"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Abstract contains controlled term: cellular senescence.","quality_checked_at":"2026-09-25T06:20:17.523592+00:00","duplicate_cluster_key":"id:nct06779032","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-02-05 to 2025-08-20","comparator":null,"confidence":"structured-source","population":"ALL · 31 Years to 61 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:14.578Z","intervention":["blood draw"],"participants":70,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["profile of leucocyte telomere length — 1 year","profile of skin examination with dermoscopic photoaging scale (DPAS) — 1 year","Profile of body mass index — 1 year","profile of p16 — 1 year","profile of waist circumference — 1 year","profile triglycerides — 1 year"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"senolytics","is_published":true,"match_reasons":["Abstract contains controlled term: cellular senescence.","Source terminology contains: cellular senescence.","Title supplies longevity context: aging.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Senolytics","slug":"senolytics"}},{"topic_slug":"skin-aging","is_published":true,"match_reasons":["Title contains controlled term: skin aging, photoaging.","Abstract contains controlled term: skin aging, photoaging.","Title supplies longevity context: aging.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Skin ageing","slug":"skin-aging"}},{"topic_slug":"telomeres-telomerase","is_published":true,"match_reasons":["Title contains controlled term: telomere.","Abstract contains controlled term: telomere.","Title supplies longevity context: aging.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Telomeres and telomerase","slug":"telomeres-telomerase"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/29208","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}