{"type":"trials","record":{"id":29284,"source_id":"clinicaltrials-gov","external_id":"NCT06082362","title":"Personalized Signature of Chronic Inflammation and Early Aging Predictive of the Comorbidities in Infertile Men","brief_summary":"The aim of the project is identify new biomarkers and/or prognostic factors in order to develop personalized strategies to prevent the onset of tumor and/or non tumor comorbidity in infertile men.","overall_status":"Unknown","phases":[],"study_type":"OBSERVATIONAL","sponsor":"IRCCS San Raffaele","enrollment":350,"countries":["Italy"],"start_date":"2023-06-21","completion_date":"2025-06-20","last_update_date":"2023-10-13","source_url":"https://clinicaltrials.gov/study/NCT06082362","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:08.862442+00:00","last_seen_at":"2026-09-25T06:05:37.656+00:00","metadata":{"sex":"MALE","acronym":null,"age_range":"18 Years to 50 Years","comparator":null,"organization":"IRCCS San Raffaele","interventions":["Collection of clinical and biological material"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Endocrine-metabolomic parameters — Baseline","Functional characterization of immune cells — Baseline","Clinical data — Baseline","Immunological outcomes — Baseline","Senescence biomarkers — Baseline"],"design_description":null,"source_has_results":false},"controlled_terms":["Male Infertility","Collection of clinical and biological material"],"relevance_confidence":80,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: chronic inflammation.","quality_checked_at":"2026-09-25T06:05:39.423355+00:00","duplicate_cluster_key":"id:nct06082362","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2023-06-21 to 2025-06-20","comparator":null,"confidence":"structured-source","population":"MALE · 18 Years to 50 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:05:37.669Z","intervention":["Collection of clinical and biological material"],"participants":350,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Endocrine-metabolomic parameters — Baseline","Functional characterization of immune cells — Baseline","Clinical data — Baseline","Immunological outcomes — Baseline","Senescence biomarkers — Baseline"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"chronic-inflammation","is_published":true,"match_reasons":["Title contains controlled term: chronic inflammation.","Title supplies longevity context: aging.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Chronic inflammation","slug":"chronic-inflammation"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/29284","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}