{"type":"trials","record":{"id":29377,"source_id":"clinicaltrials-gov","external_id":"NCT03603587","title":"Bioclinical Study of Scalp Photoaging of a Population Male Over 65 Years Old.","brief_summary":"The aging of skin, especially that of the scalp, is a combination of intrinsic and extrinsic aging factors secondary to the chronic sun exposure. For men with an alopecia genetic (= bald men), the solar part, in skin aging process, is major. The helio-dermal scalp is frequently the site of cancers mainly after 65 years. Objectives are to identify specific biomarkers involved in the photo-aging of the alopecic scalp","overall_status":"Terminated","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Centre Hospitalier Universitaire de Saint Etienne","enrollment":1,"countries":["France"],"start_date":"2019-02-14","completion_date":"2019-09-20","last_update_date":"2020-03-05","source_url":"https://clinicaltrials.gov/study/NCT03603587","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Terminated. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:08.862442+00:00","last_seen_at":"2026-09-25T06:20:14.553+00:00","metadata":{"sex":"MALE","acronym":"BACCHUS","age_range":"65 Years","comparator":null,"organization":"Centre Hospitalier Universitaire de Saint Etienne","interventions":["biopsy","blood sample","questionnaire on sun exposure","examination of the scalp","Norwood scale","questionnaire of clinicals signs","scinexa score","questionnaire of the history of the hair loss"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Scalp skin biomarkers — at the surgery (about 28 days after the inclusion)","Differential expression profile of proteomic biomarkers — 28 days","Data of thickness measurements of the 3 layers of the skin — 28 days","scalp microflora — 28 days","Percentage of anisotropy of the tensile forces of the skin — 28 days","histology — 28 days","Heterogeneity of pigmentation — 28 days","Scinexa score (SCore for INtrinsic and EXtrinsic skin Aging) — 28 days","The measurement of the thickness of the dermis — 28 days","The measurement of the morphology of the dermal junction epidermis — 28 days","Solar exposure score — 28 days","Norwood's scale — 28 days"],"design_description":"NA · SINGLE GROUP · OTHER · NONE","source_has_results":false},"controlled_terms":["Skin Aging","Skin Cancer","biopsy","blood sample","questionnaire on sun exposure","examination of the scalp","Norwood scale","questionnaire of clinicals signs","scinexa score","questionnaire of the history of the hair loss"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: photoaging.","quality_checked_at":"2026-09-25T06:20:17.523592+00:00","duplicate_cluster_key":"id:nct03603587","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2019-02-14 to 2019-09-20","comparator":null,"confidence":"structured-source","population":"MALE · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:14.596Z","intervention":["biopsy","blood sample","questionnaire on sun exposure","examination of the scalp","Norwood scale","questionnaire of clinicals signs","scinexa score","questionnaire of the history of the hair loss"],"participants":1,"study_design":"NA · SINGLE GROUP · OTHER · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Scalp skin biomarkers — at the surgery (about 28 days after the inclusion)","Differential expression profile of proteomic biomarkers — 28 days","Data of thickness measurements of the 3 layers of the skin — 28 days","scalp microflora — 28 days","Percentage of anisotropy of the tensile forces of the skin — 28 days","histology — 28 days","Heterogeneity of pigmentation — 28 days","Scinexa score (SCore for INtrinsic and EXtrinsic skin Aging) — 28 days","The measurement of the thickness of the dermis — 28 days","The measurement of the morphology of the dermal junction epidermis — 28 days","Solar exposure score — 28 days","Norwood's scale — 28 days"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"skin-aging","is_published":true,"match_reasons":["Title contains controlled term: photoaging.","Abstract contains controlled term: skin aging.","Source terminology contains: skin aging.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Skin ageing","slug":"skin-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/29377","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}