{"type":"trials","record":{"id":30099,"source_id":"clinicaltrials-gov","external_id":"NCT07732478","title":"Effects of a Community-based Multicomponent Physical Exercise Program on Physical Function, Frailty, and Sarcopenia in Older Adults From the Municipality of Santoña: a Quasi-experimental Study.","brief_summary":"This study evaluates the effects of a community-based multicomponent exercise program on physical function, frailty, and sarcopenia in older adults living in the municipality of Santoña (Cantabria, Spain). The exercise program is organized and delivered by the Santoña Town Council as part of its public health services for older residents and is not created for research purposes; it will continue regardless of the outcome of this study. Researchers are only evaluating participants who voluntarily agree to be assessed before and after each 36-week cycle of the program, over four consecutive academic years (2026-2030). The main question this study aims to answer is whether continued participation in this real-world, community-based multicomponent exercise program (based on the Vivifrail model) leads to meaningful improvements in physical function, muscle strength, and cardiorespiratory capacity, and helps reverse indicators of frailty and sarcopenia in independent, community-dwelling older adults. Participants will complete functional and physical tests, including balance, gait speed, chair-stand performance, handgrip strength, and a 6-minute walk test, at the start and end of each 36-week exercise cycle. No blood or biological samples will be collected.","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Universidad de Granada","enrollment":300,"countries":["Spain"],"start_date":"2026-10-01","completion_date":"2030-07-31","last_update_date":"2026-07-30","source_url":"https://clinicaltrials.gov/study/NCT07732478","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:16.485702+00:00","last_seen_at":"2026-09-25T07:05:20.248+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":null,"organization":"Universidad de Granada","interventions":["Multicomponent Exercise Program (Vivifrail-based)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Short Physical Performance Battery (SPPB) score — Baseline (week 0) and post-intervention (week 36), for each of the fo…","Handgrip strength — Baseline (week 0) and post-intervention (week 36), for each of the four annual cohorts (2026-2030)","30-Second Chair Stand Test — Baseline (week 0) and post-intervention (week 36), for each of the four annual cohorts (20…","6-Minute Walk Test (6MWT) distance — Baseline (week 0) and post-intervention (week 36), for each of the four annual coh…","Body weight and Body Mass Index (BMI) — Baseline (week 0) and post-intervention (week 36), for each of the four annual…","Waist circumference — Baseline (week 0) and post-intervention (week 36), for each of the four annual cohorts (2026-2030)","Self-perceived fitness (International Fitness Scale, IFIS) — Baseline (week 0) and post-intervention (week 36), for eac…"],"design_description":"NA · SINGLE GROUP · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Frailty/Sarcopenia","Frailty in Older Adults","Sarcopenia","Multicomponent Exercise Program (Vivifrail-based)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T07:05:30.295959+00:00","duplicate_cluster_key":"id:nct07732478","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-10-01 to 2030-07-31","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T07:05:20.260Z","intervention":["Multicomponent Exercise Program (Vivifrail-based)"],"participants":300,"study_design":"NA · SINGLE GROUP · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Short Physical Performance Battery (SPPB) score — Baseline (week 0) and post-intervention (week 36), for each of the fo…","Handgrip strength — Baseline (week 0) and post-intervention (week 36), for each of the four annual cohorts (2026-2030)","30-Second Chair Stand Test — Baseline (week 0) and post-intervention (week 36), for each of the four annual cohorts (20…","6-Minute Walk Test (6MWT) distance — Baseline (week 0) and post-intervention (week 36), for each of the four annual coh…","Body weight and Body Mass Index (BMI) — Baseline (week 0) and post-intervention (week 36), for each of the four annual…","Waist circumference — Baseline (week 0) and post-intervention (week 36), for each of the four annual cohorts (2026-2030)","Self-perceived fitness (International Fitness Scale, IFIS) — Baseline (week 0) and post-intervention (week 36), for eac…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise.","Abstract contains controlled term: exercise.","Source terminology contains: exercise.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}},{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}},{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/30099","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}