{"type":"trials","record":{"id":30300,"source_id":"clinicaltrials-gov","external_id":"NCT07687316","title":"Mental Effort During Low Load Resistance Training in Older Adults","brief_summary":"The goal of this clinical trial is to determine the effect of maximal mental effort combined with low-intensity resistance training on strength and neuromuscular function in older adults. The main questions it aims to answer are: * Does low-intensity resistance training in combination with maximal mental effort increase strength more than low intensity resistance training alone? * Does low-intensity resistance training in combination with maximal mental effort improve neuromuscular function more than low intensity resistance training alone? Participants will be randomly assigned to 1 of 3 groups: * Low intensity resistance training * Low intensity resistance training with maximal mental effort * Control Researchers will compare groups to determine differences in changes in strength, neuromuscular function, and body composition.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Kennesaw State University","enrollment":75,"countries":["United States"],"start_date":"2026-06-06","completion_date":"2027-12-01","last_update_date":"2026-07-08","source_url":"https://clinicaltrials.gov/study/NCT07687316","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:16.485702+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years to 85 Years","comparator":"Control","organization":"Kennesaw State University","interventions":["Low Intensity Resistance Training with Maximal Mental Effort","Low Intensity Resistance Training"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in isokinetic strength of the knee extensors at 60 degrees per second — Baseline, Week 8","Change in isokinetic knee extensor muscle activation as measured by electromyography amplitude — Baseline, Week 8","Change in isometric knee extensor strength as measured by newton-meters of torque — Baseline, Week 8","Change in knee extensor muscle activation as measured by electromyography amplitude — Baseline, Week 8","Change in motor unit firing rate as measured relative to the motor unit recruitment threshold — Baseline, Week 8","Change in motor unit action potential size as measured relative to the motor unit recruitment threshold — Baseline, Wee…","Change in handgrip strength as measured in kilograms of force — Baseline, Week 8","Change in walking speed as measured by time taken to walk 4 meters — Baseline, Week 8","Change in chair rise performance as measured by number of chair rises performed in 30 seconds — Baseline, Week 8","Change in bicep curl strength as measured by load lifted in pounds — Baseline, Week 8","Change in dynamic strength of the lower body muscles during the leg press as measured by load lifted in pounds for 5 re…","Change in muscle composition as measured by ultrasound-derived grey-scale analysis — Baseline, Week 8","Change in skeletal muscle size as measured by ultrasound-derived cross-sectional area — Baseline, Week 8","Change in fat mass as measured by kilograms — Baseline, Week 8","Change in fat-free mass as measured by kilograms — Baseline, Week 8","Change in body fat percentage as measured by fat tissue relative to fat-free tissue — Baseline, Week 8","Change in cognitive function as measured by the Montreal Cognitive Assessment — Baseline, Week 8"],"design_description":"RANDOMIZED · PARALLEL · OTHER · SINGLE","source_has_results":false},"controlled_terms":["Seniors","Old Age","Sarcopenia","Low Intensity Resistance Training with Maximal Mental Effort","Low Intensity Resistance Training"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: resistance training.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07687316","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-06-06 to 2027-12-01","comparator":"Control","confidence":"structured-source","population":"ALL · 65 Years to 85 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.770Z","intervention":["Low Intensity Resistance Training with Maximal Mental Effort","Low Intensity Resistance Training"],"participants":75,"study_design":"RANDOMIZED · PARALLEL · OTHER · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in isokinetic strength of the knee extensors at 60 degrees per second — Baseline, Week 8","Change in isokinetic knee extensor muscle activation as measured by electromyography amplitude — Baseline, Week 8","Change in isometric knee extensor strength as measured by newton-meters of torque — Baseline, Week 8","Change in knee extensor muscle activation as measured by electromyography amplitude — Baseline, Week 8","Change in motor unit firing rate as measured relative to the motor unit recruitment threshold — Baseline, Week 8","Change in motor unit action potential size as measured relative to the motor unit recruitment threshold — Baseline, Wee…","Change in handgrip strength as measured in kilograms of force — Baseline, Week 8","Change in walking speed as measured by time taken to walk 4 meters — Baseline, Week 8","Change in chair rise performance as measured by number of chair rises performed in 30 seconds — Baseline, Week 8","Change in bicep curl strength as measured by load lifted in pounds — Baseline, Week 8","Change in dynamic strength of the lower body muscles during the leg press as measured by load lifted in pounds for 5 re…","Change in muscle composition as measured by ultrasound-derived grey-scale analysis — Baseline, Week 8","Change in skeletal muscle size as measured by ultrasound-derived cross-sectional area — Baseline, Week 8","Change in fat mass as measured by kilograms — Baseline, Week 8","Change in fat-free mass as measured by kilograms — Baseline, Week 8","Change in body fat percentage as measured by fat tissue relative to fat-free tissue — Baseline, Week 8","Change in cognitive function as measured by the Montreal Cognitive Assessment — Baseline, Week 8"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"resistance-training","is_published":true,"match_reasons":["Title contains controlled term: resistance training.","Abstract contains controlled term: resistance training.","Source terminology contains: resistance training.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Resistance training","slug":"resistance-training"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/30300","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}