{"type":"trials","record":{"id":30312,"source_id":"clinicaltrials-gov","external_id":"NCT07686146","title":"Multicomponent Exercise and Frailty in Nursing Home Residents","brief_summary":"Frailty is common among older adults living in nursing homes and increases the risk of falls, disability, and loss of independence. However, there is limited evidence on practical and feasible exercise programs adapted to this population. This study evaluated the effects of a multicomponent exercise program combining strength and balance training in residents aged 65 years and older. Participants were assigned to either an intervention group, which performed supervised exercise sessions twice a week for 8 weeks, or a control group, which continued their usual activities. The main outcome was frailty, measured using the Short Physical Performance Battery. Other outcomes included balance, functional independence, sarcopenia, fear of falling, and number of falls. This study was retrospectively registered.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Escoles Universitaries Gimbernat","enrollment":66,"countries":["Spain"],"start_date":"2021-11-30","completion_date":"2022-12-31","last_update_date":"2026-07-07","source_url":"https://clinicaltrials.gov/study/NCT07686146","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:16.485702+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":"BASE-Frail","age_range":"65 Years","comparator":null,"organization":"Escoles Universitaries Gimbernat","interventions":["Multicomponent Exercise Program (BASE)","Usual Care"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Frailty assessed by the Short Physical Performance Battery (SPPB) — Baseline to 8 weeks","Balance assessed by the Performance-Oriented Mobility Assessment (POMA) — Baseline, 8 weeks, and 20 weeks","Sarcopenia assessed by SARC-F — Baseline, 8 weeks, and 20 weeks","Functional independence assessed by the Barthel Index — Baseline, 8 weeks, and 20 weeks","Fear of falling assessed by Short FES-I — Baseline, 8 weeks, and 20 weeks","Number of falls — Throughout the 20-week study period"],"design_description":"NON RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Balance Impairment","Sarcopenia in Elderly","Frailty at Older Adults","Functional Decline","Fall Risk","Multicomponent Exercise Program (BASE)","Usual Care"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct07686146","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2021-11-30 to 2022-12-31","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.770Z","intervention":["Multicomponent Exercise Program (BASE)","Usual Care"],"participants":66,"study_design":"NON RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Frailty assessed by the Short Physical Performance Battery (SPPB) — Baseline to 8 weeks","Balance assessed by the Performance-Oriented Mobility Assessment (POMA) — Baseline, 8 weeks, and 20 weeks","Sarcopenia assessed by SARC-F — Baseline, 8 weeks, and 20 weeks","Functional independence assessed by the Barthel Index — Baseline, 8 weeks, and 20 weeks","Fear of falling assessed by Short FES-I — Baseline, 8 weeks, and 20 weeks","Number of falls — Throughout the 20-week study period"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise.","Abstract contains controlled term: exercise.","Source terminology contains: exercise.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}},{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/30312","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}