{"type":"trials","record":{"id":30354,"source_id":"clinicaltrials-gov","external_id":"NCT07616219","title":"Exergaming-based Sitting Tai Chi for Sarcopenia and/or Frailty","brief_summary":"This randomized controlled trial will evaluate the effects of an exergaming-based sitting Tai Chi program on muscle strength, physical function, cognition, and psychosocial outcomes in older adults living in residential care facilities who are at risk of sarcopenia and/or prefrailty. Eligible participants aged 60 years or older will be identified using simple screening criteria for sarcopenia and prefrailty and will not meet full diagnostic criteria for sarcopenia or frailty. A total of 152 participants will be randomly assigned to either an individually supervised exergaming-based sitting Tai Chi intervention or a group-based general health education control, each delivered twice weekly for 12 weeks. The primary outcome is dominant-hand grip strength, a core indicator of sarcopenia-related muscle weakness. Key secondary outcomes include sitting balance and functional reach assessed by the Modified Functional Reach Test, with additional secondary measures of muscle mass, lower-extremity function, activities of daily living, reaction time and health-related quality of life. Outcomes will be assessed at baseline, mid-intervention, post-intervention, and 3-month follow-up. The findings will provide preliminary evidence on whether chair-based exergaming Tai Chi can be integrated into routine residential care to support healthy aging and functional independence.","overall_status":"Enrolling By Invitation","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Hong Kong Metropolitan University","enrollment":152,"countries":["Hong Kong"],"start_date":"2026-03-01","completion_date":"2027-12-31","last_update_date":"2026-07-01","source_url":"https://clinicaltrials.gov/study/NCT07616219","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Enrolling By Invitation. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:16.485702+00:00","last_seen_at":"2026-09-25T06:25:08.953+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"60 Years","comparator":"General health education","organization":"Hong Kong Metropolitan University","interventions":["Exergaming-based sitting Tai Chi","General health education"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Maximal handgrip strength — Baseline (Week 0), mid-intervention (Week 6, after 12 sessions), post-intervention (Week 12…","Sitting Balance and Functional Reach (Modified Functional Reach Test) — Baseline (Week 0), mid-intervention (Week 6, af…","Skeletal Muscle Mass Index (SMI) — Baseline (Week 0), mid-intervention (Week 6, after 12 sessions), post-intervention (…","Lower-Extremity Function (Five Times Sit-to-Stand Test) — Baseline (Week 0), mid-intervention (Week 6, after 12 session…","Independence in Activities of Daily Living (Katz ADL-C) — Baseline (Week 0), mid-intervention (Week 6, after 12 session…","Reaction Time on a Computer-Based Finger-Press Reaction Task — Baseline (Week 0), mid-intervention (Week 6, after 12 se…","Health-Related Quality of Life on the EQ-5D-5L Utility Index — Baseline (Week 0), mid-intervention (Week 6, after 12 se…"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","source_has_results":false},"controlled_terms":["Sarcopenia in Elderly","Frailty at Older Adults","Exergaming-based sitting Tai Chi","General health education"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:25:14.10514+00:00","duplicate_cluster_key":"id:nct07616219","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-03-01 to 2027-12-31","comparator":"General health education","confidence":"structured-source","population":"ALL · 60 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:08.965Z","intervention":["Exergaming-based sitting Tai Chi","General health education"],"participants":152,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Maximal handgrip strength — Baseline (Week 0), mid-intervention (Week 6, after 12 sessions), post-intervention (Week 12…","Sitting Balance and Functional Reach (Modified Functional Reach Test) — Baseline (Week 0), mid-intervention (Week 6, af…","Skeletal Muscle Mass Index (SMI) — Baseline (Week 0), mid-intervention (Week 6, after 12 sessions), post-intervention (…","Lower-Extremity Function (Five Times Sit-to-Stand Test) — Baseline (Week 0), mid-intervention (Week 6, after 12 session…","Independence in Activities of Daily Living (Katz ADL-C) — Baseline (Week 0), mid-intervention (Week 6, after 12 session…","Reaction Time on a Computer-Based Finger-Press Reaction Task — Baseline (Week 0), mid-intervention (Week 6, after 12 se…","Health-Related Quality of Life on the EQ-5D-5L Utility Index — Baseline (Week 0), mid-intervention (Week 6, after 12 se…"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}},{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Source terminology contains: sarcopenia.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/30354","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}