{"type":"trials","record":{"id":30621,"source_id":"clinicaltrials-gov","external_id":"NCT06874413","title":"Targeted Prehabilitation With Physical Exercise and Inspiratory Muscle Training for Elderly Frail Patients Prior to Ventral Hernia Repair","brief_summary":"The purpose of this study is to assess the physical fitness of patients undergoing hernia repair and correlate the postoperative outcomes and recovery as well as assess the impact of a targeted physical exercise program preoperatively in a cohort of frail, elderly patients. The investigators hypothesize that physical exercise will improve activity levels in elderly patients with frailty prior to ventral hernia repair. The investigators further hypothesize that increased levels of activity preoperatively will correlate with improved postoperative outcomes.","overall_status":"Enrolling By Invitation","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Prisma Health-Upstate","enrollment":120,"countries":["United States"],"start_date":"2025-03-19","completion_date":"2027-06-30","last_update_date":"2026-05-27","source_url":"https://clinicaltrials.gov/study/NCT06874413","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Enrolling By Invitation. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:16.485702+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":"Group 1 - Standard of Care; Group 3 - Observational Cohort","organization":"Prisma Health-Upstate","interventions":["Prehabilitation","Standard of Care (SOC)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Activity levels — 6-8 weeks preoperatively","Quality of Life Pre- and Postoperative Assessment — 14-30 days postoperatively","Quality of Life Pre- and Postoperative Outcomes — 14-30 days postoperatively","Postoperative Outcomes - Surgical Complications — 14-30 days postoperatively","Postoperative Outcomes - Length of Stay — 14-30 days postoperatively","Postoperative Outcomes - Discharge Location — 14-30 days postoperatively","Postoperative Outcomes - Return to Baseline — 14-30 days postoperatively"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Frailty","Ventral Hernia","Prehabilitation","Standard of Care (SOC)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: exercise.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct06874413","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-03-19 to 2027-06-30","comparator":"Group 1 - Standard of Care; Group 3 - Observational Cohort","confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.429Z","intervention":["Prehabilitation","Standard of Care (SOC)"],"participants":120,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Activity levels — 6-8 weeks preoperatively","Quality of Life Pre- and Postoperative Assessment — 14-30 days postoperatively","Quality of Life Pre- and Postoperative Outcomes — 14-30 days postoperatively","Postoperative Outcomes - Surgical Complications — 14-30 days postoperatively","Postoperative Outcomes - Length of Stay — 14-30 days postoperatively","Postoperative Outcomes - Discharge Location — 14-30 days postoperatively","Postoperative Outcomes - Return to Baseline — 14-30 days postoperatively"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"exercise","is_published":true,"match_reasons":["Title contains controlled term: exercise.","Abstract contains controlled term: exercise.","Title supplies longevity context: frail, elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Exercise","slug":"exercise"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/30621","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}