{"type":"trials","record":{"id":31182,"source_id":"clinicaltrials-gov","external_id":"NCT07435064","title":"NURsing-led FRAILty Prevention and Care","brief_summary":"The goal of this quasi-experimental study is to learn if a nurse-led care program can help prevent or manage frailty in older adults living in the community. The study focuses on people aged 65 years and older who have at least one chronic condition, show early signs of frailty, and have difficulty with self-care. The main questions it aims to answer are: * Does the nurse-led NUR-FRAIL program improve participants' ability to care for their chronic conditions after six months? * Does the program improve quality of life and reduce health-related difficulties? * Does the program lower emergency department visits and hospital stays over one year? Researchers will compare participants who receive the NUR-FRAIL program with participants who receive usual care to see if the program leads to better self-care, better quality of life, and less use of hospital services. Participants will: * Meet with a Family and Community Nurse for health and frailty assessments at the start of the study, after three months, and after six months * Complete short questionnaires about self-care, daily functioning, and quality of life * Receive either usual care or a three-month nurse-led program that includes personalized education, goal setting, lifestyle advice, and support for managing chronic conditions * Allow researchers to collect information about emergency visits and hospital stays for up to twelve months Some participants in the nurse-led group will also be invited to take part in an interview to share their experience with the program.","overall_status":"Not Yet Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University of Padova","enrollment":200,"countries":[],"start_date":"2026-03-01","completion_date":"2027-03-30","last_update_date":"2026-02-27","source_url":"https://clinicaltrials.gov/study/NCT07435064","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Not Yet Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:21.317971+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":"NUR-FRAIL","age_range":"65 Years","comparator":"Control","organization":"University of Padova","interventions":["NUR-FRAIL"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Self-care maintenance was assessed using the Self-Care of Chronic Illness Inventory questionnaire (minimum score = 0, m…","Self-care monitoring was assessed using the Self-Care of Chronic Illness Inventory questionnaire (minimum score = 0, ma…","Self-care management was assessed using the Self-Care of Chronic Illness Inventory questionnaire (minimum score = 0, ma…","Self-perceived patient complexity was assessed using the INTERMED questionnaire (minimum score = 0, maximum score = 60)…","Quality of life was assessed using the 12-Item Short Form Health Survey (SF-12) (minimum score = 0, maximum score = 100…","Number of emergency department access by patient — six and 12 months","Number of hospitalization by patient — six and 12 months"],"design_description":"NON RANDOMIZED · PARALLEL · TREATMENT · NONE","source_has_results":false},"controlled_terms":["Chronic Conditions","NUR-FRAIL"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct07435064","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2026-03-01 to 2027-03-30","comparator":"Control","confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.459Z","intervention":["NUR-FRAIL"],"participants":200,"study_design":"NON RANDOMIZED · PARALLEL · TREATMENT · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Self-care maintenance was assessed using the Self-Care of Chronic Illness Inventory questionnaire (minimum score = 0, m…","Self-care monitoring was assessed using the Self-Care of Chronic Illness Inventory questionnaire (minimum score = 0, ma…","Self-care management was assessed using the Self-Care of Chronic Illness Inventory questionnaire (minimum score = 0, ma…","Self-perceived patient complexity was assessed using the INTERMED questionnaire (minimum score = 0, maximum score = 60)…","Quality of life was assessed using the 12-Item Short Form Health Survey (SF-12) (minimum score = 0, maximum score = 100…","Number of emergency department access by patient — six and 12 months","Number of hospitalization by patient — six and 12 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/31182","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}