{"type":"trials","record":{"id":31233,"source_id":"clinicaltrials-gov","external_id":"NCT05107947","title":"Light in Frail Elderly - the Effect of a Dynamic Light for Sleep and Circadian Rhythm","brief_summary":"The aim of this project is to evaluate the effect of a dynamic light in order to improve the circadian rhythm, provide a better sleep and well-being, and in the long run an improved recovery. The primary question is whether dynamic artificial light with circadian stimulus can affect the circadian rhythm. The secondary question is whether this also provides better sleep and well-being. The group that is particularly interesting to study is a geriatric population that is more sensitive to circadian rhythm disorders, sleep disorders and confusion in connection with hospitalization and that can be of particular benefit from this intervention.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Region Skane","enrollment":300,"countries":["Sweden"],"start_date":"2022-10-31","completion_date":"2028-09-01","last_update_date":"2026-01-12","source_url":"https://clinicaltrials.gov/study/NCT05107947","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:21.317971+00:00","last_seen_at":"2026-09-25T06:25:39.067+00:00","metadata":{"sex":"ALL","acronym":"LIFE","age_range":"65 Years","comparator":"Control standard light environment","organization":"Region Skane","interventions":["Biocentric light"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Melatonin curve — Change after three days of biocentric light exposure","Sleep — Increased total sleep time after three days of biocentric light exposure"],"design_description":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · NONE","source_has_results":false},"controlled_terms":["Aged","Circadian Rhythm","Cognition","Fatigue","Humans","Light","Melatonin","Sleep","Biocentric","Frailty","Karolinska Sleepiness Score","Inflammation","Biocentric light"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":85,"publication_state":"published","match_explanation":"Title contains controlled term: circadian rhythm.","quality_checked_at":"2026-09-25T06:25:42.287439+00:00","duplicate_cluster_key":"id:nct05107947","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2022-10-31 to 2028-09-01","comparator":"Control standard light environment","confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:39.094Z","intervention":["Biocentric light"],"participants":300,"study_design":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Melatonin curve — Change after three days of biocentric light exposure","Sleep — Increased total sleep time after three days of biocentric light exposure"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"circadian-rhythms","is_published":true,"match_reasons":["Title contains controlled term: circadian rhythm.","Abstract contains controlled term: circadian rhythm.","Source terminology contains: circadian rhythm.","Title supplies longevity context: frail, elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Circadian rhythms","slug":"circadian-rhythms"}},{"topic_slug":"sleep","is_published":true,"match_reasons":["Title contains controlled term: sleep, circadian.","Abstract contains controlled term: sleep, circadian.","Source terminology contains: sleep, circadian.","Title supplies longevity context: frail, elderly.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sleep","slug":"sleep"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/31233","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}