{"type":"trials","record":{"id":31553,"source_id":"clinicaltrials-gov","external_id":"NCT01280903","title":"Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension","brief_summary":"The purpose of the Staying Active with Arthritis (STAR) research study is to determine if a 6-month program will improve leg exercise, fitness walking, and clinical outcomes (function, blood pressure, leg strength, pain, fatigue, and health-related quality of life) in older adults with osteoarthritis of the knee and high blood pressure.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University of Pittsburgh","enrollment":182,"countries":["United States"],"start_date":"2012-01-01","completion_date":"2015-04-01","last_update_date":"2024-09-19","source_url":"https://clinicaltrials.gov/study/NCT01280903","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:21.317971+00:00","last_seen_at":"2026-09-25T06:25:08.953+00:00","metadata":{"sex":"ALL","acronym":"STAR","age_range":"50 Years","comparator":"Attention-Control","organization":"University of Pittsburgh","interventions":["STAR Intervention","Attention-Control"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Performance of Lower Extremity Exercise at 25 Weeks — At the end of the 6-month intervention period (week 25)","Participation in Fitness Walking at 25 Weeks — At the end of the 6-month intervention period (week 25)","Objective Functional Status by the 6-minute Walk at 25 Weeks — At the end of the 6-month intervention period (week 25)","Objective Functional Status by the Short Physical Performance Battery at 25 Weeks — At the end of the 6-month intervent…","Systolic Blood Pressure at 25 Weeks — At the end of the 6-month intervention period (week 25)","Diastolic Blood Pressure at 25 Weeks — At the end of the 6-month intervention period (week 25)","Performance of Lower Extremity Exercise at 52 Weeks — 6 months after the intervention period ends (week 52)","Participation in Fitness Walking at 52 Weeks — 6 months after the intervention period ends (week 52)","Objective Functional Status by the 6-minute Walk at 52 Weeks — 6 months after the intervention period ends (week 52)","Objective Functional Status by the Short Physical Performance Battery at 52 Weeks — 6 months after the intervention per…","Systolic Blood Pressure at 52 Weeks — 6 months after the intervention period ends (week 52)","Diastolic Blood Pressure at 52 Weeks — 6 months after the intervention period ends (week 52)","Subjective Functional Status at 25 Weeks — At the end of the 6-month intervention period (week 25)","Quadriceps Strength at 25 Weeks — At the end of the 6-month intervention period (week 25)","Pain by the Pain Subscale of the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index at 25 Weeks — A…","Pain by the Bodily Pain Subscale of the Short Form-36v2 at 25 Weeks — At the end of the 6-month intervention period (we…","Fatigue at 25 Weeks — At the end of the 6-month intervention period (week 25)","Health-Related Quality of Life at 25 Weeks — At the end of the 6-month intervention period (week 25)","Self-Efficacy at 25 Weeks — At the end of the 6-month intervention period (week 25)","Arthritis Self-Efficacy at 25 Weeks — At the end of the 6-month intervention period (week 25)"],"design_description":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","source_has_results":true},"controlled_terms":["Osteoarthritis, Knee","Hypertension","STAR Intervention","Attention-Control"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: osteoarthritis.","quality_checked_at":"2026-09-25T06:25:14.10514+00:00","duplicate_cluster_key":"id:nct01280903","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2012-01-01 to 2015-04-01","comparator":"Attention-Control","confidence":"structured-source","population":"ALL · 50 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:25:09.008Z","intervention":["STAR Intervention","Attention-Control"],"participants":182,"study_design":"RANDOMIZED · PARALLEL · TREATMENT · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Performance of Lower Extremity Exercise at 25 Weeks — At the end of the 6-month intervention period (week 25)","Participation in Fitness Walking at 25 Weeks — At the end of the 6-month intervention period (week 25)","Objective Functional Status by the 6-minute Walk at 25 Weeks — At the end of the 6-month intervention period (week 25)","Objective Functional Status by the Short Physical Performance Battery at 25 Weeks — At the end of the 6-month intervent…","Systolic Blood Pressure at 25 Weeks — At the end of the 6-month intervention period (week 25)","Diastolic Blood Pressure at 25 Weeks — At the end of the 6-month intervention period (week 25)","Performance of Lower Extremity Exercise at 52 Weeks — 6 months after the intervention period ends (week 52)","Participation in Fitness Walking at 52 Weeks — 6 months after the intervention period ends (week 52)","Objective Functional Status by the 6-minute Walk at 52 Weeks — 6 months after the intervention period ends (week 52)","Objective Functional Status by the Short Physical Performance Battery at 52 Weeks — 6 months after the intervention per…","Systolic Blood Pressure at 52 Weeks — 6 months after the intervention period ends (week 52)","Diastolic Blood Pressure at 52 Weeks — 6 months after the intervention period ends (week 52)","Subjective Functional Status at 25 Weeks — At the end of the 6-month intervention period (week 25)","Quadriceps Strength at 25 Weeks — At the end of the 6-month intervention period (week 25)","Pain by the Pain Subscale of the Western Ontario and McMaster Universities (WOMAC) Osteoarthritis Index at 25 Weeks — A…","Pain by the Bodily Pain Subscale of the Short Form-36v2 at 25 Weeks — At the end of the 6-month intervention period (we…","Fatigue at 25 Weeks — At the end of the 6-month intervention period (week 25)","Health-Related Quality of Life at 25 Weeks — At the end of the 6-month intervention period (week 25)","Self-Efficacy at 25 Weeks — At the end of the 6-month intervention period (week 25)","Arthritis Self-Efficacy at 25 Weeks — At the end of the 6-month intervention period (week 25)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"joint-cartilage-aging","is_published":true,"match_reasons":["Title contains controlled term: osteoarthritis.","Abstract contains controlled term: osteoarthritis.","Source terminology contains: osteoarthritis.","Title supplies longevity context: older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Joint and cartilage ageing","slug":"joint-cartilage-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/31553","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}