{"type":"trials","record":{"id":32007,"source_id":"clinicaltrials-gov","external_id":"NCT07080086","title":"The Effect of Preoperative Biological Age on Hemodynamics and Renal Function","brief_summary":"Background The aim of this study is to explore the potential value of preoperative biological age as a predictor of intraoperative hemodynamic changes and postoperative renal function injury. Methods Collect data using medical record system and surgical anesthesia system, and gather patients who have undergone surgery. Calculate the preoperative biological age of the patient and analyze the correlation between preoperative biological age accelerated aging and intraoperative hemodynamics and postoperative renal function damage.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Nanjing First Hospital, Nanjing Medical University","enrollment":268833,"countries":[],"start_date":"2015-01-01","completion_date":"2024-07-30","last_update_date":"2025-07-23","source_url":"https://clinicaltrials.gov/study/NCT07080086","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:23.954312+00:00","last_seen_at":"2026-09-25T06:15:13.984+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":null,"comparator":null,"organization":"Nanjing First Hospital, Nanjing Medical University","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["The incidence ofn AKI — Within 7 days postoperative,","The incidence of AKD — Within 8-90 days post-surgery","The incidence of IOH — During intraoperative period","The incidence of PIH — From induction of general anesthesia to 20 minutes post-induction.","The incidence of AKI 2+ — 0-7 days post-surgery","Cumulative duration of IOH and PIH — During surgery","The cumulative AUC of IOH and PIH. — During surgery"],"design_description":null,"source_has_results":false},"controlled_terms":["Acute Kidney Injury","Acute Kidney Disease","Intraoperative Hypotension","Post-induction Hypotension"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: biological age.","quality_checked_at":"2026-09-25T06:15:15.562724+00:00","duplicate_cluster_key":"id:nct07080086","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2015-01-01 to 2024-07-30","comparator":null,"confidence":"structured-source","population":"ALL","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:15:14.003Z","intervention":[],"participants":268833,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["The incidence ofn AKI — Within 7 days postoperative,","The incidence of AKD — Within 8-90 days post-surgery","The incidence of IOH — During intraoperative period","The incidence of PIH — From induction of general anesthesia to 20 minutes post-induction.","The incidence of AKI 2+ — 0-7 days post-surgery","Cumulative duration of IOH and PIH — During surgery","The cumulative AUC of IOH and PIH. — During surgery"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"biological-age-biomarkers","is_published":true,"match_reasons":["Title contains controlled term: biological age.","Abstract contains controlled term: biological age.","Title supplies longevity context: biological age.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Biological age biomarkers","slug":"biological-age-biomarkers"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/32007","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}