{"type":"trials","record":{"id":32014,"source_id":"clinicaltrials-gov","external_id":"NCT07035470","title":"Biological Age Predicts 90-Day Mortality in Advanced Cancer","brief_summary":"This retrospective study evaluates whether biological age, calculated using the PhenoAge model, predicts short-term outcomes in patients with advanced cancer who were hospitalized. The main goal is to investigate associations between biological age and short-term mortality, functional status (ECOG), comorbidity burden (mCCI), and length of hospital stay. All data were collected from medical records without any patient intervention.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Ankara Etlik City Hospital","enrollment":1615,"countries":["Turkey (Türkiye)"],"start_date":"2022-11-05","completion_date":"2024-12-31","last_update_date":"2025-06-29","source_url":"https://clinicaltrials.gov/study/NCT07035470","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:23.954312+00:00","last_seen_at":"2026-09-25T06:15:13.984+00:00","metadata":{"sex":"ALL","acronym":"BIOAGE-CAN","age_range":null,"comparator":null,"organization":"Ankara Etlik City Hospital","interventions":["PhenoAge-Based Biological Age Assessment"],"registry_source":"ClinicalTrials.gov","outcome_measures":["90-Day All-Cause Mortality — Up to 90 days post-admission","Modified Charlson Comorbidity Index (mCCI) — Baseline (Day of hospital admission)"],"design_description":null,"source_has_results":false},"controlled_terms":["Advanced Solid Tumors Cancer","Hospitalizations","PhenoAge-Based Biological Age Assessment"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Abstract contains controlled term: phenoage.","quality_checked_at":"2026-09-25T06:15:15.562724+00:00","duplicate_cluster_key":"id:nct07035470","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2022-11-05 to 2024-12-31","comparator":null,"confidence":"structured-source","population":"ALL","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:15:14.003Z","intervention":["PhenoAge-Based Biological Age Assessment"],"participants":1615,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["90-Day All-Cause Mortality — Up to 90 days post-admission","Modified Charlson Comorbidity Index (mCCI) — Baseline (Day of hospital admission)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"biological-age-biomarkers","is_published":true,"match_reasons":["Title contains controlled term: biological age.","Abstract contains controlled term: biological age.","Source terminology contains: biological age.","Title supplies longevity context: biological age.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Biological age biomarkers","slug":"biological-age-biomarkers"}},{"topic_slug":"epigenetic-clocks","is_published":true,"match_reasons":["Abstract contains controlled term: phenoage.","Source terminology contains: phenoage.","Title supplies longevity context: biological age.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Epigenetic clocks","slug":"epigenetic-clocks"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/32014","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}