{"type":"trials","record":{"id":32051,"source_id":"clinicaltrials-gov","external_id":"NCT06761274","title":"Study of Epigenetic and Inflammatory Markers of Accelerated Biological Ageing in the Follow up of Patients With Hodgkin's Lymphoma","brief_summary":"Study design: It is a monocentric and exploratory study, experimental on human tissues in vitro which involves the analysis of peripheral blood in patients with Hodgkin's lymphomas with the following characteristics: * in complete remission for at least two years after first-line therapy with stage IIb, III or IV at onset (Ann Arbor classification). * newly diagnosed (stage IIb, III or IV, Ann Arbor Classification).","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","enrollment":200,"countries":["Italy"],"start_date":"2022-11-03","completion_date":"2025-09-30","last_update_date":"2025-01-07","source_url":"https://clinicaltrials.gov/study/NCT06761274","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:23.954312+00:00","last_seen_at":"2026-09-25T06:15:13.984+00:00","metadata":{"sex":"ALL","acronym":"MEPI-AGE","age_range":"18 Years","comparator":null,"organization":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","interventions":["peripheral blood sampling"],"registry_source":"ClinicalTrials.gov","outcome_measures":["evaluation of senescence markers (CD57, KLRG1,CD62L, CD45RA) — through study completion, an average of 2 year","DNA methylation (methylation rate) — through study completion, an average of 2 year"],"design_description":"NA · SINGLE GROUP · HEALTH SERVICES RESEARCH · NONE","source_has_results":false},"controlled_terms":["Hodgkin Lymphoma in Remission","peripheral blood sampling"],"relevance_confidence":80,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: biological age.","quality_checked_at":"2026-09-25T06:15:15.562724+00:00","duplicate_cluster_key":"id:nct06761274","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2022-11-03 to 2025-09-30","comparator":null,"confidence":"structured-source","population":"ALL · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:15:14.004Z","intervention":["peripheral blood sampling"],"participants":200,"study_design":"NA · SINGLE GROUP · HEALTH SERVICES RESEARCH · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["evaluation of senescence markers (CD57, KLRG1,CD62L, CD45RA) — through study completion, an average of 2 year","DNA methylation (methylation rate) — through study completion, an average of 2 year"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"biological-age-biomarkers","is_published":true,"match_reasons":["Title contains controlled term: biological age.","Title supplies longevity context: ageing, biological age.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Biological age biomarkers","slug":"biological-age-biomarkers"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/32051","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}