{"type":"trials","record":{"id":32166,"source_id":"clinicaltrials-gov","external_id":"NCT05588921","title":"LensAge to Reveal Biological Age","brief_summary":"Assessment of aging is central to health management. Compared to chronological age, biological age can better reflect the aging process and health status; however, an effective indicator of biological age in clinical practice is lacking. Human lens accumulates biological changes during aging and is amenable to a rapid and objective assessment. Therefore, the investigators will develop LensAge as an innovative indicator to reveal biological age based on deep learning using lens photographs.","overall_status":"Unknown","phases":[],"study_type":"OBSERVATIONAL","sponsor":"Sun Yat-sen University","enrollment":6000,"countries":["China"],"start_date":"2020-01-01","completion_date":"2022-12-30","last_update_date":"2022-10-21","source_url":"https://clinicaltrials.gov/study/NCT05588921","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:23.954312+00:00","last_seen_at":"2026-09-25T06:15:13.984+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"20 Years to 100 Years","comparator":null,"organization":"Sun Yat-sen University","interventions":[],"registry_source":"ClinicalTrials.gov","outcome_measures":["The difference between LensAge and chronological age — Baseline","Correlation between the LensAge difference and age-related health parameters — Baseline","Mean absolute error (MAE) of the DL age estimation model. — Baseline","Mean error (ME) of the DL age estimation model. — Baseline","R-squared (R2) of the DL age estimation model. — Baseline"],"design_description":null,"source_has_results":false},"controlled_terms":["Ophthalmology","Lens Opacities","Biological Age"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: biological age.","quality_checked_at":"2026-09-25T06:15:15.562724+00:00","duplicate_cluster_key":"id:nct05588921","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2020-01-01 to 2022-12-30","comparator":null,"confidence":"structured-source","population":"ALL · 20 Years to 100 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:15:14.008Z","intervention":[],"participants":6000,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["The difference between LensAge and chronological age — Baseline","Correlation between the LensAge difference and age-related health parameters — Baseline","Mean absolute error (MAE) of the DL age estimation model. — Baseline","Mean error (ME) of the DL age estimation model. — Baseline","R-squared (R2) of the DL age estimation model. — Baseline"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"biological-age-biomarkers","is_published":true,"match_reasons":["Title contains controlled term: biological age.","Abstract contains controlled term: biological age.","Source terminology contains: biological age.","Title supplies longevity context: biological age.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Biological age biomarkers","slug":"biological-age-biomarkers"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/32166","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}