{"type":"trials","record":{"id":32172,"source_id":"clinicaltrials-gov","external_id":"NCT05535608","title":"Targeting the Nine Hallmarks of Aging on DNA Methylation","brief_summary":"SRW Laboratories has formulated the Cel System protocol, a group of three formulas designed to interact with each of the 9 Hallmarks of Aging and combined this with an App that supports positive lifestyle changes, with a view that, if we can positively impact each Hallmark, we can support healthy aging.","overall_status":"Unknown","phases":["PHASE2"],"study_type":"INTERVENTIONAL","sponsor":"TruDiagnostic","enrollment":50,"countries":["United States"],"start_date":"2022-08-15","completion_date":"2023-12-31","last_update_date":"2022-09-10","source_url":"https://clinicaltrials.gov/study/NCT05535608","editorial_summary":"A registered PHASE2 study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:23.954312+00:00","last_seen_at":"2026-09-25T06:15:13.984+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"55 Years to 90 Years","comparator":null,"organization":"TruDiagnostic","interventions":["SRW Cel System"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Biological age — Change in epigenetic age from baseline to 12 months","Inflammatory marker IL-6 — Change in inflammatory marker from baseline to 12 months","C-reactive protein — Change in inflammatory marker from baseline to 12 months"],"design_description":"NON RANDOMIZED · SINGLE GROUP · PREVENTION · NONE","source_has_results":false},"controlled_terms":["Aging","SRW Cel System"],"relevance_confidence":80,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: dna methylation.","quality_checked_at":"2026-09-25T06:15:15.562724+00:00","duplicate_cluster_key":"id:nct05535608","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2022-08-15 to 2023-12-31","comparator":null,"confidence":"structured-source","population":"ALL · 55 Years to 90 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:15:14.008Z","intervention":["SRW Cel System"],"participants":50,"study_design":"NON RANDOMIZED · SINGLE GROUP · PREVENTION · NONE","subject_scope":"Human clinical study registration","evidence_stage":"PHASE2","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Biological age — Change in epigenetic age from baseline to 12 months","Inflammatory marker IL-6 — Change in inflammatory marker from baseline to 12 months","C-reactive protein — Change in inflammatory marker from baseline to 12 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"epigenetic-alterations","is_published":true,"match_reasons":["Title contains controlled term: dna methylation.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Epigenetic alterations","slug":"epigenetic-alterations"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/32172","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}