{"type":"trials","record":{"id":32202,"source_id":"clinicaltrials-gov","external_id":"NCT02903992","title":"SArcopenia Prevalence in Frail Older Adults. SAF Study","brief_summary":"The age-associated loss of lean mass is a defining parameter of sarcopenia and may lead to various negative health outcomes such as impairment of physical performance and disability. Furthermore sarcopenia is considered to be one of the main factors in the pathogenesis of the frailty syndrome. However, for clinical use and for treatment and prevention strategies, reliable diagnostic criteria and cutpoints based on clinically relevant thresholds are indispensable. This topic has recently been addressed by the Foundation for the National Institutes of Health Sarcopenia Project which identified cutpoints for appendicular lean mass (ALM) below which older adults had a higher likelihood of clinically relevant weakness reflected by low grip strength. Moreover, a low ALM-to-body mass index (BMI) ratio (\\<0.789 men and \\<0.512 women) was found to be associated with increased likelihood for mobility impairment. In this context, the aim of this study is to study the prevalence of sarcopenia in a sample of community-dwelling frail and pre-frail older adults.","overall_status":"Completed","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University Hospital, Toulouse","enrollment":225,"countries":["France"],"start_date":"2016-05-01","completion_date":"2019-12-01","last_update_date":"2021-10-29","source_url":"https://clinicaltrials.gov/study/NCT02903992","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:16:23.954312+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":"SAF","age_range":"70 Years","comparator":null,"organization":"University Hospital, Toulouse","interventions":["Dual-energy X-ray absorptiometry (DXA)"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Sarcopenia Diagnostic with Dual-energy X-ray absorptiometry — one day (participation of subject)","(SPPB) score — one day (participation of subject)","(MMSE) score — one day (participation of subject)","(MNA) score — one day (participation of subject)","(IADL) score — one day (participation of subject)"],"design_description":"NA · SINGLE GROUP · DIAGNOSTIC · NONE","source_has_results":false},"controlled_terms":["Aging","Dual-energy X-ray absorptiometry (DXA)"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":50,"publication_state":"published","match_explanation":"Title contains controlled term: sarcopenia.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct02903992","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2016-05-01 to 2019-12-01","comparator":null,"confidence":"structured-source","population":"ALL · 70 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.875Z","intervention":["Dual-energy X-ray absorptiometry (DXA)"],"participants":225,"study_design":"NA · SINGLE GROUP · DIAGNOSTIC · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Sarcopenia Diagnostic with Dual-energy X-ray absorptiometry — one day (participation of subject)","(SPPB) score — one day (participation of subject)","(MMSE) score — one day (participation of subject)","(MNA) score — one day (participation of subject)","(IADL) score — one day (participation of subject)"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"sarcopenia","is_published":true,"match_reasons":["Title contains controlled term: sarcopenia.","Abstract contains controlled term: sarcopenia.","Title supplies longevity context: frail, older adult.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Sarcopenia","slug":"sarcopenia"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/32202","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}