{"type":"trials","record":{"id":33018,"source_id":"clinicaltrials-gov","external_id":"NCT05262036","title":"The Effects of a Longevity Supplement on Aging and Photoaging","brief_summary":"This study evaluates the use of an oral supplement to see if it can shift the function of the skin and the appearance of fine lines and wrinkles, its impact on biomarkers associated with aging, and its impact on mental health.","overall_status":"Unknown","phases":[],"study_type":"INTERVENTIONAL","sponsor":"Integrative Skin Science and Research","enrollment":38,"countries":["United States"],"start_date":"2022-08-04","completion_date":"2023-12-31","last_update_date":"2023-10-23","source_url":"https://clinicaltrials.gov/study/NCT05262036","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Unknown. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:06.962668+00:00","last_seen_at":"2026-09-25T06:20:14.553+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"35 Years to 70 Years","comparator":"Placebo excipients","organization":"Integrative Skin Science and Research","interventions":["Anti-aging Supplement","Placebo"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Appearance of Fine Lines and Wrinkles — 6 months","Appearance of facial redness — 6 months","Appearance of facial pigmentation — 6 months","Appearance of facial texture — 6 months","Skin hydration — 6 months","Skin elasticity — 6 months","Fasting lipids — 6 months","Hemoglobin A1c — 6 months","Ultra-sensitive CRP — 6 months","Blood pressure — 6 months","Mental health survey — 6 months","Subjective skin health survey — 6 months","Epigenetic signals — 6 months"],"design_description":"RANDOMIZED · PARALLEL · OTHER · NONE","source_has_results":false},"controlled_terms":["Photoaging","Anti-aging Supplement","Placebo"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: photoaging.","quality_checked_at":"2026-09-25T06:20:17.523592+00:00","duplicate_cluster_key":"id:nct05262036","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2022-08-04 to 2023-12-31","comparator":"Placebo excipients","confidence":"structured-source","population":"ALL · 35 Years to 70 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:20:14.586Z","intervention":["Anti-aging Supplement","Placebo"],"participants":38,"study_design":"RANDOMIZED · PARALLEL · OTHER · NONE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Appearance of Fine Lines and Wrinkles — 6 months","Appearance of facial redness — 6 months","Appearance of facial pigmentation — 6 months","Appearance of facial texture — 6 months","Skin hydration — 6 months","Skin elasticity — 6 months","Fasting lipids — 6 months","Hemoglobin A1c — 6 months","Ultra-sensitive CRP — 6 months","Blood pressure — 6 months","Mental health survey — 6 months","Subjective skin health survey — 6 months","Epigenetic signals — 6 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"skin-aging","is_published":true,"match_reasons":["Title contains controlled term: photoaging.","Source terminology contains: photoaging.","Title supplies longevity context: aging, longevity.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Skin ageing","slug":"skin-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/33018","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}