{"type":"trials","record":{"id":34352,"source_id":"clinicaltrials-gov","external_id":"NCT02751866","title":"Early Intervention in Cognitive Aging","brief_summary":"Nutritional intervention in overweight middle aged individuals with subjective memory complaints.","overall_status":"Active Not Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University of Cincinnati","enrollment":250,"countries":["United States"],"start_date":"2016-01-01","completion_date":"2026-06-01","last_update_date":"2025-04-01","source_url":"https://clinicaltrials.gov/study/NCT02751866","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:17.421904+00:00","last_seen_at":"2026-09-25T06:10:45.89+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"50 Years to 65 Years","comparator":"Active supplement, low carbohydrate; Placebo, Control","organization":"University of Cincinnati","interventions":["Berry fruit powder OR nutritional ketosis","Placebo powder OR higher carbohydrate"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Insulin resistance — Eight or 12 weeks after enrollment","Cognitive function — Eight or 12 weeks after enrollment","Long term glucose concentration — Eight or 12 weeks after enrollment"],"design_description":"RANDOMIZED · PARALLEL · PREVENTION · DOUBLE","source_has_results":false},"controlled_terms":["Overweight, Obesity and Other Hyperalimentation (E65-E68)","Berry fruit powder OR nutritional ketosis","Placebo powder OR higher carbohydrate"],"relevance_confidence":80,"source_quality_score":100,"freshness_score":65,"publication_state":"published","match_explanation":"Title contains controlled term: cognitive aging.","quality_checked_at":"2026-09-25T06:10:48.460085+00:00","duplicate_cluster_key":"id:nct02751866","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2016-01-01 to 2026-06-01","comparator":"Active supplement, low carbohydrate; Placebo, Control","confidence":"structured-source","population":"ALL · 50 Years to 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:45.904Z","intervention":["Berry fruit powder OR nutritional ketosis","Placebo powder OR higher carbohydrate"],"participants":250,"study_design":"RANDOMIZED · PARALLEL · PREVENTION · DOUBLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Insulin resistance — Eight or 12 weeks after enrollment","Cognitive function — Eight or 12 weeks after enrollment","Long term glucose concentration — Eight or 12 weeks after enrollment"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"cognitive-aging","is_published":true,"match_reasons":["Title contains controlled term: cognitive aging.","Title supplies longevity context: aging.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Cognitive ageing","slug":"cognitive-aging"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34352","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}