{"type":"trials","record":{"id":34617,"source_id":"clinicaltrials-gov","external_id":"NCT06988176","title":"Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery","brief_summary":"The goal of this observational study is to learn if simple tests for frailty and muscle strength can help predict which older adults (age 65 and older) are at higher risk for problems after major abdominal surgery. The main questions it aims to answer are: * Do measures of frailty and muscle strength, taken before surgery, predict complications after surgery? * Can these tests be easily done during a routine pre-surgical visit? Participants will: * Complete brief tests measuring muscle strength, breathing strength, physical function, nutrition status, body composition, and memory during a regular pre-surgical clinic appointment. * Allow researchers to review their medical records 30 and 90 days after surgery to identify any complications or health problems.","overall_status":"Completed","phases":[],"study_type":"OBSERVATIONAL","sponsor":"University of North Carolina, Chapel Hill","enrollment":100,"countries":["United States"],"start_date":"2025-06-19","completion_date":"2026-08-04","last_update_date":"2026-08-17","source_url":"https://clinicaltrials.gov/study/NCT06988176","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Completed. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years","comparator":null,"organization":"University of North Carolina, Chapel Hill","interventions":["Frailty assessment, nutrition assessment, cognition assessment, muscle strength testing"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Feasibility of Frailty Assessment Integration — At the time of the preoperative assessment","Predictive Capability of Frailty Measures for Postoperative Complications — 30 and 90 days postoperatively"],"design_description":null,"source_has_results":false},"controlled_terms":["Frailty","Sarcopenia","Sarcopenia in Elderly","Muscle Strength","Post Operative Complications","Nutrition Assessment","Risk Assessment","Elderly (People Aged 65 or More)","Hand Strength","Frailty assessment, nutrition assessment, cognition assessment, muscle strength testing"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct06988176","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-06-19 to 2026-08-04","comparator":null,"confidence":"structured-source","population":"ALL · 65 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.760Z","intervention":["Frailty assessment, nutrition assessment, cognition assessment, muscle strength testing"],"participants":100,"study_design":"OBSERVATIONAL","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Feasibility of Frailty Assessment Integration — At the time of the preoperative assessment","Predictive Capability of Frailty Measures for Postoperative Complications — 30 and 90 days postoperatively"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Source terminology contains: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as OBSERVATIONAL."],"matched_fields":["title","abstract","controlled terminology","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34617","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}