{"type":"trials","record":{"id":34827,"source_id":"clinicaltrials-gov","external_id":"NCT07167277","title":"The Impact of Whey Protein on Frailty in Older Adults Classified as Pre-frail","brief_summary":"This pilot study aims to determine the impact of whey protein supplementation on brain antioxidant levels and to assess the effects of whey protein supplementation on physical function, body composition, and cognition in pre-frail older adults.","overall_status":"Active Not Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"University of Kansas Medical Center","enrollment":20,"countries":["United States"],"start_date":"2025-12-05","completion_date":"2026-09-01","last_update_date":"2026-05-14","source_url":"https://clinicaltrials.gov/study/NCT07167277","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Active Not Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:07.378+00:00","metadata":{"sex":"ALL","acronym":null,"age_range":"65 Years to 85 Years","comparator":"Placebo","organization":"University of Kansas Medical Center","interventions":["Whey Protein","Placebo"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in brain glutathione (GSH) levels measured using MRI scans. — Changes from baseline to 3 months.","Assess the change in physical function by measuring balance resistance, sit-to-stand, muscle strength and performance.…","Assess body composition with a bioelectrical impedance analysis (BIA) device. — Changes from baseline to 3 months.","Assess cognition using the NIH Toolbox cognition battery. — Changes from baseline to 3 months."],"design_description":"RANDOMIZED · PARALLEL · PREVENTION · TRIPLE","source_has_results":false},"controlled_terms":["Pre-frail","Pre-Frail Older Adults","Cognition","Physical Function","Dietary Intake Assessment","MRI","Whey Protein","Placebo"],"relevance_confidence":80,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:20.034853+00:00","duplicate_cluster_key":"id:nct07167277","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2025-12-05 to 2026-09-01","comparator":"Placebo","confidence":"structured-source","population":"ALL · 65 Years to 85 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:07.432Z","intervention":["Whey Protein","Placebo"],"participants":20,"study_design":"RANDOMIZED · PARALLEL · PREVENTION · TRIPLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in brain glutathione (GSH) levels measured using MRI scans. — Changes from baseline to 3 months.","Assess the change in physical function by measuring balance resistance, sit-to-stand, muscle strength and performance.…","Assess body composition with a bioelectrical impedance analysis (BIA) device. — Changes from baseline to 3 months.","Assess cognition using the NIH Toolbox cognition battery. — Changes from baseline to 3 months."],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","title context","study type"],"relevance_score":80,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34827","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}