{"type":"trials","record":{"id":34843,"source_id":"clinicaltrials-gov","external_id":"NCT06011499","title":"Internet-Based Lifestyle Intervention to Eradicate Obese Frailty in Prostate Cancer Survivors, iLIVE","brief_summary":"This clinical trial tests the effectiveness of an online weight loss plus resistance training intervention (iLIVE) to decrease obesity and improve frailty in men with prostate cancer who received androgen deprivation therapy (ADT). Androgen deprivation therapy increases the risk of frailty, weight gain and obesity in prostate cancer survivors. The combination of frailty and obesity can lead to a decrease in quality of life and an increased risk of recurrent falls. Using iLIVE may improve obesity and frailty in men with prostate cancer who receive ADT.","overall_status":"Recruiting","phases":[],"study_type":"INTERVENTIONAL","sponsor":"OHSU Knight Cancer Institute","enrollment":250,"countries":["United States"],"start_date":"2024-03-12","completion_date":"2027-12-31","last_update_date":"2026-05-08","source_url":"https://clinicaltrials.gov/study/NCT06011499","editorial_summary":"A registered study indexed because it matched monitored longevity research terms. Registry status: Recruiting. Registration does not establish safety or effectiveness.","first_seen_at":"2026-09-25T01:20:20.087268+00:00","last_seen_at":"2026-09-25T06:10:25.747+00:00","metadata":{"sex":"ALL","acronym":"iLIVE","age_range":"18 Years","comparator":"Arm II (usual care)","organization":"OHSU Knight Cancer Institute","interventions":["Internet-Based Exercise Intervention","Internet-Based Diet Intervention","Education Intervention"],"registry_source":"ClinicalTrials.gov","outcome_measures":["Change in overweight/obesity — At baseline, 3 months, 6 months and 12 months","Change in sarcopenia — At baseline and 6 months","Change in slowness — At baseline, 3 months and 6 months","Change in weakness — At baseline, 3 months, and 6 months","Change in inactivity — At baseline, 3 months, 6 months, and 12 months","Change in fatigue — At baseline, 3 months, 6 months, and 12 months","Change in health behaviors — At baseline, 3 months, 6 months, and 12 months","Change in physical functioning — At baseline, 3 months, 6 months, 12 months","Change in quality of life — At baseline, 3 months, 6 months, and 12 months"],"design_description":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · SINGLE","source_has_results":false},"controlled_terms":["Prostate Carcinoma","Internet-Based Exercise Intervention","Internet-Based Diet Intervention","Education Intervention"],"relevance_confidence":100,"source_quality_score":100,"freshness_score":100,"publication_state":"published","match_explanation":"Title contains controlled term: frailty.","quality_checked_at":"2026-09-25T06:10:37.875473+00:00","duplicate_cluster_key":"id:nct06011499","duplicate_of_id":null,"evidence_snapshot":{"status":"structured","version":1,"duration":"2024-03-12 to 2027-12-31","comparator":"Arm II (usual care)","confidence":"structured-source","population":"ALL · 18 Years","provenance":{"duration":"start_date and completion_date","comparator":"registry arm fields","population":"registry eligibility fields","intervention":"registry intervention fields","participants":"enrollment","study_design":"study_type and registry design fields","evidence_stage":"phases","reported_outcome":"not available","outcomes_measured":"registry outcome-measure fields"},"generated_at":"2026-09-25T06:10:25.782Z","intervention":["Internet-Based Exercise Intervention","Internet-Based Diet Intervention","Education Intervention"],"participants":250,"study_design":"RANDOMIZED · PARALLEL · SUPPORTIVE CARE · SINGLE","subject_scope":"Human clinical study registration","evidence_stage":"Phase not reported","safety_context":"Eligibility, adverse-event details, and clinical decisions must be checked in the official registry and with qualified clinicians.","source_support":"Structured registry protocol metadata; no finding-level conclusion is generated.","main_limitation":"This is a study registration. No reusable structured result is available here, so it cannot show whether the intervention worked or was safe.","reported_outcome":null,"outcomes_measured":["Change in overweight/obesity — At baseline, 3 months, 6 months and 12 months","Change in sarcopenia — At baseline and 6 months","Change in slowness — At baseline, 3 months and 6 months","Change in weakness — At baseline, 3 months, and 6 months","Change in inactivity — At baseline, 3 months, 6 months, and 12 months","Change in fatigue — At baseline, 3 months, 6 months, and 12 months","Change in health behaviors — At baseline, 3 months, 6 months, and 12 months","Change in physical functioning — At baseline, 3 months, 6 months, 12 months","Change in quality of life — At baseline, 3 months, 6 months, and 12 months"],"regulatory_context":"Trial registration is not regulatory approval and does not establish that an intervention is available."},"clinical_trial_topics":[{"topic_slug":"frailty","is_published":true,"match_reasons":["Title contains controlled term: frailty.","Abstract contains controlled term: frailty.","Title supplies longevity context: frailty, frail.","Study type is explicitly identified as INTERVENTIONAL."],"matched_fields":["title","abstract","title context","study type"],"relevance_score":100,"intelligence_topics":{"name":"Frailty","slug":"frailty"}}],"content_sources":{"name":"ClinicalTrials.gov","homepage_url":"https://clinicaltrials.gov/"}},"canonical_url":"https://www.immortal.life/trials/34843","automation_disclosure":"Generated automatically from cited source metadata. No scientist, clinician, researcher, editor, or human reviewer evaluates this publication before release."}